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Phalloidin–Atto Rho6G
suitable for fluorescence, ≥90% (HPCE)
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| Rozmiar/SKU | Dostępność | Cena netto |
|---|---|---|
10 nmol | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 2820,00 zł |
Informacje o tej pozycji
NACRES:
NA.32
UNSPSC Code:
12352116
2820,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
Pomoc techniczna
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Pozwól nam pomócQuality Segment
assay
≥90% (HPCE)
form
solid
mol wt
Mw 1396 g/mol
manufacturer/tradename
ATTO-TEC GmbH
fluorescence
λex 535 nm; λem 560 nm in 0.1 M phosphate pH 7.0
suitability
suitable for fluorescence
storage temp.
−20°C
General description
Atto Rho6G is a novel fluorescent label that belongs to the class of Rhodamine dyes. It shows a strong absorption, extraordinary high fluorescence quantum yield, high thermal and photostability, and a very little triplet formation. Atto Rho6G is moderately hydrophilic.Phalloidin is a fungal toxin isolated from the poisonous mushroom Amanita phalloides. Its toxicity is attributed to the ability to bind F-actin in liver and muscle cells. As a result of binding phalloidin, actin filaments become strongly stabilized. Phalloidin has been found to bind only to polymeric and oligomeric forms of actin, and not to monomeric actin. The dissociation constant of the actin-phalloidin complex has been determined to be on the order of 3 x 10–8. Phalloidin differs from amanitin in rapidity of action; at high dose levels, death of mice or rats occurs within 1 or 2 hours.
Application
Fluorescent conjugates of phalloidin, rhodamine-phalloidin staining reagents, such as Phalloidin–Atto Rho6G are used to label actin filaments for histological applications. Some structural features of phalloidin are required for the binding to actin. However, the side chain of amino acid 7 (g-dihydroxyleucine) is accessible for chemical modifications without appreciable loss of affinity for actin.
Legal Information
This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.
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Ta pozycja | |||
|---|---|---|---|
| description suitable for fluorescence, ≥90% (HPCE) | description suitable for fluorescence | description BioReagent, suitable for fluorescence, ≥80% (HPLC) | description BioReagent, suitable for fluorescence, ≥90% (HPLC) |
| suitability suitable for fluorescence | suitability suitable for fluorescence | suitability suitable for fluorescence | suitability suitable for fluorescence |
| fluorescence λex 535 nm; λem 560 nm in 0.1 M phosphate pH 7.0 | fluorescence - | fluorescence - | fluorescence - |
| form solid | form solid | form - | form - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| assay ≥90% (HPCE) | assay ≥90% (HPLC) | assay ≥80% (HPLC) | assay ≥90% (HPLC) |
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