95144

Retinol

BioXtra, ≥97.5% (HPLC), ~3100 U/mg

• Synonim(y): Axerophthol, Vitamin A, Vitamin A alcohol, Vitamin A₁, all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
• Wzór empiryczny (zapis Hilla): C₂₀H₃₀O
• Numer CAS: 68-26-8
• Masa cząsteczkowa: 286.45
• NACRES: NA.28
• PubChem Substance ID: 57653654
• eCl@ss: 34058018
• UNSPSC Code: 12352205
• EC Number: 200-683-7
• MDL number: MFCD00001552
• Beilstein/REAXYS Number: 403040

Właściwości

• biological source: synthetic
• Quality Segment: 200
• product line: BioXtra
• assay: ≥97.5% (HPLC)
• form: (Powder or Powder with Lumps)
• specific activity: ~3100 U/mg
• shelf life: limited shelf life
• color: faint yellow to very dark yellow
• mp: 56-61 °C, 61-63 °C (lit.)
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO)=C(C)CCC1
• InChI: 1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
• InChI key: FPIPGXGPPPQFEQ-OVSJKPMPSA-N

Opis

General description

Retinol or vitamin A alcohol is the main circulating form of vitamin A.

Application

Retinol has been used:

• as a standard in peak identification and quantification in reverse phase HPLC
• as a standard to estimate the concentration of vitamin A
• to study the inhibitory effect of retinol on murine norovirus (MNV) replication in murine RAW 264.7 cells
• as a component in the reaction mixture for the lecithin:retinol acyltransferase (LRAT) assay

Biochem/physiol Actions

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.
Retinol is biological active in a wide range of processes.

It is not biologically active and works as a precursor of active retinoids. Retinol is converted to retinaldehyde and subsequently to retinoic acid.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

1 U corresponds to 1 international U acc. to Ph Eur II, 217 (1983)

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08,GHS07
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H317,H319,H360FD,H413
• Ostrzeżenia: P202 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Aquatic Chronic 4 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Co się dzieje?: WGK 1
• PPE (środki ochrony indywidualnej): dust mask type N95 (US), Eyeshields, Gloves