B2929

B-Lymphocyte Chemoattractant human

≥95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• Synonim(y): B-Cell Attracting Chemokine 1, BCA-1, BLC
• UNSPSC Code: 12352202
• NACRES: NA.32
• MDL number: MFCD01867020
• Biological source: human
• Recombinant: expressed in E. coli
• Assay: ≥95% (SDS-PAGE)
• Form: lyophilized powder
• Mol wt: apparent mol wt 8.7 kDa by SDS-PAGE (reducing)
• Impurities: endotoxin, tested

Właściwości

• biological source: human
• Quality Segment: 200
• recombinant: expressed in E. coli
• assay: ≥95% (SDS-PAGE)
• form: lyophilized powder
• potency: 0.1000 μg/mL
• mol wt: apparent mol wt 8.7 kDa by SDS-PAGE (reducing)
• packaging: pkg of 25 μg
• storage condition: avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• UniProt accession no.: O43927
• storage temp.: −20°C
• Gene Information: human ... CXCL13(10563)

Opis

Biochem/physiol Actions

BCA-1 is a potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils.

BCA-1 is a potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils. Its specific receptor BLR1 is a G protein-coupled receptor originally isolated from Burkitt′s lymphoma cells. Among cells of the hematopoietic lineages, the expression of BRL1, now designated CXCR5, is restricted to B lymphocytes and a subpopulation of T helper memory cells.

Potent chemoattractant for B lymphocytes, but not T lymphocytes, monocytes, or neutrophils.

The biological activity of human BLC/BCA-1 is measured by its ability to chemoattract mouse BaF/3 cells transfected with human CXCR5.

Physical form

Lyophilized from a 0.2 μm filtered solution in 35% acetonitrile and 0.1% TFA containing 50 μg bovine serum albumin per 1 μg of cytokine.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H302 + H332,H319
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Ostrzeżenia: P261 - P264 - P271 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338