B3936

BAY R3401

≥98% (HPLC), solid

• Synonim(y): 4-(2-Chlorophenyl)-1-ethyl-2-methyl-5-oxo-1,4,5,7-tetrahydrofuro[3,4-b]pyridine-3-carboxylic acid isopropyl ester
• Wzór empiryczny (zapis Hilla): C₂₀H₂₂ClNO₄
• Numer CAS: 100276-03-7
• Masa cząsteczkowa: 375.85
• NACRES: NA.77
• PubChem Substance ID: 24891741
• UNSPSC Code: 12352200
• MDL number: MFCD08705409
• Assay: ≥98% (HPLC)
• Form: solid

Właściwości

• assay: ≥98% (HPLC)
• form: solid
• color: white
• solubility: DMSO: 15 mg/mL
• originator: Bayer
• storage temp.: 2-8°C
• SMILES string: CCN1C(C)=C(C(c2ccccc2Cl)C3=C1COC3=O)C(=O)OC(C)C
• InChI: 1S/C20H22ClNO4/c1-5-22-12(4)16(20(24)26-11(2)3)17(13-8-6-7-9-14(13)21)18-15(22)10-25-19(18)23/h6-9,11,17H,5,10H2,1-4H3
• InChI key: NPUSXSOBPNHOPH-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

BAY R3401 is a glycogen phosphorylase inhibitor. The racemic prodrug, BAY R3401, suppresses hepatic glycogenolysis. BAY W1807, the active metabolite of BAY R3401, inhibits muscle glycogen phosphorylase a and b. It has been investigated that the metabolites of BAY R3401 suppress hepatic glycogenolysis by allosteric inhibition and dephosphorylation of phosphorylase a.

Glycogen phosphorylase inhibitor.

Features and Benefits

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

Light sensitive; store in amber vials.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H302
• Ostrzeżenia: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): dust mask type N95 (US), Eyeshields, Gloves