C9498

CL-82198

≥98% (HPLC), powder

• Synonim(y): N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide
• Wzór empiryczny (zapis Hilla): C₁₇H₂₂N₂O₃
• Numer CAS: 307002-71-7
• Masa cząsteczkowa: 302.37
• NACRES: NA.77
• PubChem Substance ID: 329775209
• UNSPSC Code: 12352200
• MDL number: MFCD12828877
• eCl@ss: 32150313
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: DMSO: >10 mg/mL
• originator: Wyeth
• storage temp.: 2-8°C
• SMILES string: O=C(NCCCCN1CCOCC1)c2cc3ccccc3o2
• InChI: 1S/C17H22N2O3/c20-17(16-13-14-5-1-2-6-15(14)22-16)18-7-3-4-8-19-9-11-21-12-10-19/h1-2,5-6,13H,3-4,7-12H2,(H,18,20)
• InChI key: KUJQEQAVMNFFAO-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

CL-82198 is a selective inhibitor of MMP-13 that displays no activity at MMP-1, MMP-9 or TACE. It is also a selective S1′ pocket binder, binding within the entire S1′ pocket of MMP-13, docking with the morpholine ring adjacent to the catalytic zinc atom without zinc chelation.

CL-82198 is a selective inhibitor of MMP-13 that displays no activity at MMP-1, MMP-9 or TACE. It is also a selective S1′ pocket binder.

Features and Benefits

This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H302
• Ostrzeżenia: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Klasa składowania: 11 - Combustible Solids
• WGK: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable