D4297

Deoxycholic acid

BioXtra, ≥98% (HPLC)

• Synonim(y): 3α,12α-Dihydroxy-5β-cholanic acid, 7-Deoxycholic acid, Desoxycholic acid
• Wzór empiryczny (zapis Hilla): C₂₄H₄₀O₄
• Numer CAS: 83-44-3
• Masa cząsteczkowa: 392.57
• EC Number: 201-478-5
• UNSPSC Code: 12161900
• PubChem Substance ID: 24893857
• Beilstein/REAXYS Number: 3219882
• MDL number: MFCD00003673

Właściwości

• biological source: bovine bile (ex gall bladder)
• description: anionic
• product line: BioXtra
• assay: ≥98% (HPLC)
• form: powder
• mol wt: micellar avg mol wt 1200-5000
• aggregation number: 3-12
• impurities: ≤0.005% Phosphorus (P), ≤0.1% Insoluble matter
• ign. residue: ≤0.1%
• CMC: 2-6
• mp: 171-174 °C (lit.)
• cation traces: Al: ≤0.001%, Ca: ≤0.01%, Cu: ≤0.0005%, Fe: ≤0.005%, K: ≤0.005%, Mg: ≤0.005%, NH₄⁺: ≤0.05%, Na: ≤0.02%, Pb: ≤0.001%, Zn: ≤0.0005%
• HLB: 16
• functional group: carboxylic acid
• shipped in: ambient
• storage temp.: room temp
• SMILES string: C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
• InChI: 1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1
• InChI key: KXGVEGMKQFWNSR-LLQZFEROSA-N
• Gene Information: human ... ATIC(471)

Opis

General description

Deoxycholic acid is a bile acid that may affect intracellular signaling and gene expression.

Application

Deoxycholic acid has been used in a study to assess how physiological concentrations of ursodeoxycholic acid (UDCA) vs. deoxycholic acid (DCA) affect barrier function in mouse intestinal tissue. It has also been used in a study to characterize bile formation in a mouse model with hepatic disruption of the cytochrome p450 (CYP) oxidoreductase gene.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H302,H315,H319,H335
• Ostrzeżenia: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Narządy docelowe: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): dust mask type N95 (US), Eyeshields, Gloves