G2174

β-Glucuronidase from limpets (Patella vulgata)

aqueous solution, ≥85,000 units/mL

• Synonim(y): β-D-Glucuronide glucuronosohydrolase
• Numer CAS: 9001-45-0
• UNSPSC Code: 12352204
• NACRES: NA.54
• Numer WE: 3.2.1.31 (BRENDA, IUBMB)
• MDL number: MFCD00130629
• Specific activity: ≥85,000 units/mL
• Biological source: limpet (Patella vulgata)

Właściwości

• Quality Segment: 200
• biological source: limpet (Patella vulgata)
• form: aqueous solution
• specific activity: ≥85,000 units/mL
• secondary activity: ≤7,500 units/mL sulfatase
• storage temp.: 2-8°C

Opis

Application

New Technical Article Comparing Performance of Different Enzymes
Learn more about recent application data generated by Sigma R&D to optimize hydrolysis for different drug classes using enzymes from different sources and the use of a chromatographicaly purified enzyme to reduce the effect of esterase activity resulting in conversion of 6-MAM to Morphine

The enzyme from patella vulgata is reported to be more effective in hydrolyzing opioid-glucuronides than the Helix pomatia, bovine liver and E. coli enzymes

Features and Benefits

Save time with no reconstitution in this convenient liquid format.

Physical form

Aqueous solution in 0.9% NaCl with 0.02% sodium azide as preservative.

Other Notes

One Sigma or modified Fishman unit will liberate 1.0 μg of phenolphthalein from phenolphthalein glucuronide per hr at 37 °C at pH 3.8 (30 min assay).

Sulfatase Unit Definition: One unit of sulfatase will hydrolyze 1.0 μmole p-nitrocatechol sulfate per hr at pH 5.0 at 37 °C.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS08
• signalword: Danger
• hcodes: H334
• pcodes: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Klasa składowania: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable