M2946

Mosapride citrate salt dihydrate

≥98% (HPLC), solid, 5-HT₄ receptor agonist

• Synonim(y): 4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl ]-2-morpholinyl]methyl]benzamide citrate dihydrate
• Wzór empiryczny (zapis Hilla): C₂₁H₂₅ClFN₃O₃ · C₆H₈O₇ · 2H₂O
• Numer CAS: 636582-62-2
• Masa cząsteczkowa: 650.05
• UNSPSC Code: 12352200
• PubChem Substance ID: 329817957
• NACRES: NA.77
• MDL number: MFCD00874415
• Assay: ≥98% (HPLC)
• Form: solid

Właściwości

• Nazwa produktu: Mosapride citrate salt dihydrate,
• assay: ≥98% (HPLC)
• Quality Segment: 100
• form: solid
• solubility: DMSO: ≥5 mg/mL
• originator: Takeda
• storage temp.: 2-8°C
• SMILES string: O.O.OC(=O)CC(O)(CC(O)=O)C(O)=O.CCOc1cc(N)c(Cl)cc1C(=O)NCC2CN(CCO2)Cc3ccc(F)cc3
• InChI: 1S/C21H25ClFN3O3.C6H8O7.2H2O/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14;7-3(8)1-6(13,5(11)12)2-4(9)10;;/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);2*1H2
• InChI key: KVKIQHMTGSGTFO-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

5-HT₄ receptor agonist and 5-HT₃ receptor antagonist

Mosapride is found effective against chronic gastritis, functional dyspepsia and gastro-oesophageal reflux disease. It is useful in treating many other symptoms associated with gastrointestinal disorders. Mosapride is known to improve digestive motility.

Features and Benefits

This compound was developed by Takeda. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS05
• signalword: Danger
• hcodes: H318
• pcodes: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves