M6807

Misoprostol

≥99% (HPLC)

• Synonim(y): (±)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E₁ methyl ester
• Wzór empiryczny (zapis Hilla): C₂₂H₃₈O₅
• Numer CAS: 59122-46-2
• Masa cząsteczkowa: 382.53
• NACRES: NA.77
• PubChem Substance ID: 24897117
• UNSPSC Code: 12352211
• MDL number: MFCD00274550

Właściwości

• Quality Segment: 200
• assay: ≥99% (HPLC)
• form: liquid
• functional group: ester
• storage temp.: −20°C
• SMILES string: CCCCC(C)(O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC
• InChI: 1S/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3/b12-10+/t17-,18-,20-,22?/m1/s1
• InChI key: OJLOPKGSLYJEMD-URPKTTJQSA-N
• Gene Information: human ... PTGER3(5733), PTGIR(5739)

Opis

Biochem/physiol Actions

Cytoprotective PGE₁ analog that prevents NSAID-induced gastric ulceration.

PGE₁ analog prodrug which is rapidly de-esterified to active "misoprostolic acid". Cited for extremely wide-ranging therapeutic effects, including prevention of NSAID-induced gastric ulceration, regulation of immunologic cascades, inhibition of platelet-activating factor (PAF), treatment of ethanol- and acetaminophen-induced hepatotoxicity and hepatitis, and stimulation of cartilage repair after injury.

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Informacja o środkach bezpieczeństwa

• Temperatura zapłonu (°F): Not applicable
• Piktogramy: GHS06,GHS08
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H301,H360
• Ostrzeżenia: P201 - P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral - Repr. 1B
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°C): Not applicable