MAK296

Monoamine Oxidase-B Inhibitor Screening Kit (Fluorometric)

sufficient for 100 fluorometric tests

• Synonim(y): MAO-B Inhibitor Fluorometric Assay Kit
• NACRES: NA.25
• UNSPSC Code: 12161503

Właściwości

• detection method: fluorometric
• relevant disease(s): neurological disorders
• storage temp.: −20°C

Opis

General description

The new Monoamine Oxidase (MAO) Inhibitor Screening Kit, MAK520, is now available! Monoamine oxidases (MAO, EC 1.4.3.4) are a family of enzymes that can oxidize a wide variety of endogenous primary amines. Two isoforms, MAO-A and MAO-B, have been identified based on their substrate, inhibitor specificity and tissue localization. MAO-B can oxidize primary amines, but its list of specific substrates (i.e. benzylamine, phenylethylamine) is more limited compared to MAO-A.

Application

Suitable for screening/studying/characterizing MAO-B inhibitors.

Biochem/physiol Actions

This MAO-B Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of MAO-B inhibitors. The assay is based on the fluorometric detection of H₂O₂, one of the byproducts generated during the oxidative deamination of the MAO substrate (tyramine).

Features and Benefits

Compatible with high-throughput handling systems.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08,GHS07
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H302,H334,H336
• Ostrzeżenia: P261 - P264 - P271 - P284 - P301 + P312 - P403 + P233
• Hazard Classifications: Acute Tox. 4 Oral - Resp. Sens. 1 - STOT SE 3
• Narządy docelowe: Central nervous system
• Klasa składowania: 10 - Combustible liquids
• Co się dzieje?: WGK 3