N4396

Nalbuphine hydrochloride hydrate

≥98% (HPLC), powder, μ and κ opioid receptors agonist

• Synonim(y): 17-(Cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride hydrate
• Wzór empiryczny (zapis Hilla): C₂₁H₂₇NO₄ · HCl · xH₂O
• Numer CAS: 23277-43-2
• Masa cząsteczkowa: 393.90 (anhydrous basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278052
• NACRES: NA.77
• EC Number: 245-549-9
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Nazwa produktu: Nalbuphine hydrochloride hydrate, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• drug control: regulated under CDSA - not available from Sigma-Aldrich Canada
• solubility: H₂O: soluble, ethanol: soluble
• originator: Abbott
• SMILES string: Cl[H].[H]O[H].[H][C@@]12Oc3c(O)ccc4C[C@H]5N(CC[C@@]1(c34)[C@@]5(O)CC[C@@H]2O)CC6CCC6
• InChI: 1S/C21H27NO4.ClH.H2O/c23-14-5-4-13-10-16-21(25)7-6-15(24)19-20(21,17(13)18(14)26-19)8-9-22(16)11-12-2-1-3-12;;/h4-5,12,15-16,19,23-25H,1-3,6-11H2;1H;1H2/t15-,16+,19-,20-,21+;;/m0../s1
• InChI key: IUGXDRGXUYNFHK-XSFMULHUSA-N
• Gene Information: human ... OPRD1(4985), OPRK1(4986), OPRM1(4988)

Opis

General description

Nalbuphine functions as an analgesic. It has anti catabolic properties. Nalbuphine maybe associated with sedation, nausea and vomiting.

Biochem/physiol Actions

Partial agonist for μ and κ opioid receptors.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H300 + H310 + H330
• Ostrzeżenia: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Oral
• Klasa składowania: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Co się dzieje?: WGK 3
• PPE (środki ochrony indywidualnej): Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges