Merck
  • P4405
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P4405

Sigma-Aldrich

Podophyllotoxin

Empirical Formula (Hill Notation):
C22H22O8
CAS Number:
Molecular Weight:
414.41
Beilstein:
99163
Numer EC:
Numer MDL:
Identyfikator substancji w PubChem:
NACRES:
NA.77

Próba

≥98%

Poziom jakości

forma

powder

mp

183-184 °C (lit.)

temp. przechowywania

2-8°C

SMILES string

COc1cc(cc(OC)c1OC)[C@H]2C3C(COC3=O)[C@@H](O)c4cc5OCOc5cc24

InChI

1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1

InChI key

YJGVMLPVUAXIQN-XVVDYKMHSA-N

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1 of 4

This Item
O1877Y0002002T9576
Podophyllotoxin

Sigma-Aldrich

P4405

Podophyllotoxin

Ochratoxin A from Petromyces albertensis, ≥98% (HPLC)

Sigma-Aldrich

O1877

Ochratoxin A

Podophyllotoxin European Pharmacopoeia (EP) Reference Standard

Y0002002

Podophyllotoxin

Picropodophyllotoxin ≥96% (HPLC), powder

Sigma-Aldrich

T9576

Picropodophyllotoxin

assay

≥98%

assay

≥98% (HPLC)

assay

-

assay

≥96% (HPLC)

form

powder

form

powder

form

-

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

200

Quality Level

300

Quality Level

-

Quality Level

100

mp

183-184 °C (lit.)

mp

-

mp

183-184 °C (lit.)

mp

-

Zastosowanie

Podophyllotoxin has been used as a reference compound for evaluating the cytotoxicity in VERO cells. It has also been used as a reference standard in high-performance liquid chromatography (HPLC).

Działania biochem./fizjol.

Podophyllotoxin is a naturally occurring lignan obtained from resin podophyllin present in the genus Podophyllum. It exhibits antiviral and antimitotic properties. Podophyllotoxin may be used to treat anogenital warts in children and dermatological conditions caused by psoriasis vulgaris. It may also be used as a therapeutic agent to treat genital tumors, Wilms tumors, lung cancer, and lymphomas.
Inhibits microtubule assembly; antineoplastic.

piktogramy

Skull and crossbones

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

Klasyfikacja zagrożeń

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organy docelowe

Respiratory system

Kod klasy składowania

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Temperatura zapłonu °F

Not applicable

Temperatura zapłonu °C

Not applicable

Środki ochrony indywidualnej

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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