P7547

Phentolamine hydrochloride

≥98% (TLC), α-adrenoceptor antagonist, powder

• Synonim(y): 2-[N-(3-Hydroxyphenyl)-p-toluidinomethyl]-2-imidazolidine hydrochloride, 3-[[(4,5-Dihydro-1H-imidazol-2-yl)-methyl](4-methylphenyl)-amino]-phenol monohydrochloride
• Wzór empiryczny (zapis Hilla): C₁₇H₁₉N₃O · HCl
• Numer CAS: 73-05-2
• Masa cząsteczkowa: 317.81
• NACRES: NA.77
• PubChem Substance ID: 24898856
• UNSPSC Code: 12352116
• EC Number: 200-793-5
• MDL number: MFCD00079268
• Beilstein/REAXYS Number: 3764617
• Assay: ≥98% (TLC)
• Form: powder

Właściwości

• Nazwa produktu: Phentolamine hydrochloride, ≥98% (TLC), powder
• Quality Segment: 200
• assay: ≥98% (TLC)
• form: powder
• color: white to off-white
• solubility: ethanol: 14 mg/mL, H₂O: 20 mg/mL, H₂O: unstable (prepare immediately prior to use)
• originator: Novartis
• SMILES string: Cl[H].Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3
• InChI: 1S/C17H19N3O.ClH/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H
• InChI key: TUEJFGFQYKDAPM-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

Opis

Biochem/physiol Actions

α-adrenoceptor antagonist; peripheral vasodilator.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Protect From Light.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H302
• Ostrzeżenia: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): dust mask type N95 (US), Eyeshields, Gloves