R7017

Resazurin sodium salt

powder, BioReagent

• Synonim(y): 7-Hydroxy-3H-phenoxazin-3-one-10-oxide sodium salt
• Wzór empiryczny (zapis Hilla): C₁₂H₆NNaO₄
• Numer CAS: 62758-13-8
• Masa cząsteczkowa: 251.17
• UNSPSC Code: 12352207
• NACRES: NA.75
• PubChem Substance ID: 24899387
• EC Number: 263-718-5
• Beilstein/REAXYS Number: 3794971
• MDL number: MFCD00005036

Właściwości

• product line: BioReagent
• Quality Segment: 200
• form: powder
• composition: Dye content, ~80%
• pH: 3.8-6.5, orange to violet
• solubility: H₂O: soluble
• λmax: 600 nm
• SMILES string: [Na+].[O-]c1ccc2c(OC3=CC(=O)C=CC3=[N+]2[O-])c1
• InChI: 1S/C12H7NO4.Na/c14-7-1-3-9-11(5-7)17-12-6-8(15)2-4-10(12)13(9)16;/h1-6,14H;/q;+1/p-1
• InChI key: IVGPGQSSDLDOLH-UHFFFAOYSA-M

Opis

Application

For the measurement of metabolic activity and proliferation of living cells. The bioreduction of the dye reduces the amount of the oxidized form (blue) and concomitantly increases the fluorescent intermediate (red).

Resazurin sodium salt has been used in viability assay:

• to measure cell viability of A. fumigatus
• to assess cell proliferation
• to determine A. fumigatus viability in high-throughput screenings of microbial natural extracts

Biochem/physiol Actions

Resazurin is a blue, non-fluorescent dye originally used to test milk/biological fluids for bacterial and yeast contamination. It is also useful in sperm viability and semen quality test. Resazurin is applicable in cytotoxicity determination.

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Informacja o środkach bezpieczeństwa

• PPE (środki ochrony indywidualnej): dust mask type N95 (US), Eyeshields, Gloves
• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H315,H319,H335
• Ostrzeżenia: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Narządy docelowe: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable