RAB0361

Human MMP-1 ELISA Kit

for serum, plasma, cell culture supernatant and urine

• Synonim(y): MMP-1, Matrix metalloproteinase-1
• NACRES: NA.32
• UNSPSC Code: 41116158
• Gene information: human ... MMP1(4312)
• Input: sample type plasma; sample type cell culture supernatant(s); sample type serum; sample type urine
• Species reactivity: human
• Storage temp.: −20°C
• Shipped in: wet ice

Właściwości

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable, capture ELISA: suitable
• input: sample type plasma; sample type cell culture supernatant(s); sample type serum; sample type urine
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 8 pg/mL; standard curve range: 24.69-18000 pg/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... MMP1(4312)

Opis

General description

The Human MMP-1 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MMP-1 pro and active forms in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human MMP1

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human MMP-1 ELISA Kit has been used in ELISA assays.

Biochem/physiol Actions

Matrix metalloproteinases (MMPs) enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-1 is a secreted collagenase with specificity toward Type I, II, III, VII, and X collagens, aggrecan, serpins, and α2-macroglobulin. It is overexpressed in lumbar intervertebral disc degeneration (IDD). It might also be associated with osteoarthritis. MMP-1 is linked with juvenile idiopathic arthritis. Genetic variations in MMP-1 can affect the susceptibility and severity of this disease.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Elementy zestawu są też dostępne oddzielnie

• RABELADE

  ELISA 5X Assay/Sample Diluent Buffer E (Item E2)

  Karta charakterystyki
• RABSTOP3

  ELISA Stop Solution (Item I)

  Karta charakterystyki
• RABTMB3

  ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)

  Karta charakterystyki
• RABWASH4

  20X Wash Buffer (Item B)

  Karta charakterystyki

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08
• Słowo ostrzegawcze: Danger
• Klasa składowania: 12 - Non Combustible Liquids
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Kody zagrożeń: H334
• Ostrzeżenia: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1