S2812

SNC80

≥98% (HPLC), δ opioid receptor agonist, solid

• Synonim(y): (+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide, SNC 80, SNC-80
• Wzór empiryczny (zapis Hilla): C₂₈H₃₉N₃O₂
• Numer CAS: 156727-74-1
• Masa cząsteczkowa: 449.63
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278698
• NACRES: NA.77
• MDL number: MFCD00672673
• Assay: ≥98% (HPLC)
• Form: solid

Właściwości

• Nazwa produktu: SNC80, ≥98% (HPLC), solid
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• color: off-white
• solubility: DMSO: soluble
• SMILES string: CCN(CC)C(=O)c1ccc(cc1)[C@H](N2C[C@H](C)N(CC=C)C[C@H]2C)c3cccc(OC)c3
• InChI: 1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27?/m0/s1
• InChI key: KQWVAUSXZDRQPZ-QNWUEUMSSA-N
• Gene Information: human ... OPRD1(4985) ; mouse ... Oprd1(18386) ; rat ... Oprd1(24613), Oprm1(25601)

Opis

Application

Rats were administered SNC80 to study the role of nitric oxide synthase in peripheral antinociception mechanism.⁵

Biochem/physiol Actions

SNC80 is a δ opioid receptor agonist.

SNC80 is a highly selective agonist of δ opioid receptor but also binds to μ-δ opioid receptor heteromers to produce antinociception in mice.² It also acts as anti-depressant³, elicits dopamine-related behaviors and enhances behavioral responses to psychostimulants.⁴

Features and Benefits

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): Eyeshields, Gloves, type N95 (US)