This product should be stored in 2-8°C in powdered format. The solution can be stored at 2-8°C for several weeks or at -20°C for more extended periods.
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S4014
Spectinomycin dihydrochloride pentahydrate
powder, suitable for cell culture and plant cell culture, BioReagent
Synonim(y):
Spectinomycin
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| Rozmiar/SKU | Dostępność | Cena netto |
|---|---|---|
5 g | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 1190,00 zł |
25 g | Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności | 2440,00 zł |
Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C14H24N2O7 · 2HCl · 5H2O
Numer CAS:
Masa cząsteczkowa:
495.35
NACRES:
NA.76
PubChem Substance ID:
UNSPSC Code:
12352207
EC Number:
244-554-3
MDL number:
1190,00 zł
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
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Pozwól nam pomócNazwa produktu
Spectinomycin dihydrochloride pentahydrate, powder, BioReagent, suitable for cell culture
biological source
synthetic (inorganic)
Quality Segment
product line
BioReagent
form
powder
potency
≥603 μg per mg
storage condition
(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
technique(s)
cell culture | mammalian: suitable, cell culture | plant: suitable
impurities
endotoxin, tested
color
white to pale buff
solubility
H2O: soluble 50 mg/mL at
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
application(s)
agriculture
mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
O.O.O.O.O.Cl.Cl.CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O
InChI
1S/C14H24N2O7.2ClH.5H2O/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;;;;;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H;5*1H2/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;;;;;;/m1......./s1
InChI key
DCHJOVNPPSBWHK-UXXUFHFZSA-N
General description
Spectinomycin has generally been used for the treatment of gonorrhea in males, and a study conducted shows that spectinomycin dihydrochloride pentahydrate provides effective treatment against gonorrhea as well. Clinically, spectinomycin dihydrochloride pentahydrate is easier to use in injections as it shows higher solubility than spectinomycin.
Chemical structure: aminoglycoside
Application
Spectinomycin dihydrochloride pentahydrate has been used as a supplement in different types of media.
Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by Pasteurella multocida and Mannheimia haemolytica, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.
Biochem/physiol Actions
Mode of Action: Spectinomycin acts by inhibiting protein synthesis and elongation by binding to the bacterial 30S ribosomal subunit and interfering with peptidyl tRNA translocation.
Mode of Resistance: A mutation in rpsE, the gene for ribosomal protein S5, prevents the binding of spectinomycin. Resistance is also conferred by the aminoglycoside-3′-adenyltransferase gene (aadA).
Antimicrobial spectrum: Spectinomycin acts against gram-negative and gram-positive bacteria.
Mode of Resistance: A mutation in rpsE, the gene for ribosomal protein S5, prevents the binding of spectinomycin. Resistance is also conferred by the aminoglycoside-3′-adenyltransferase gene (aadA).
Antimicrobial spectrum: Spectinomycin acts against gram-negative and gram-positive bacteria.
Preparation Note
Stock solutions should be prepared at 10 mg/mL in water and filter sterilized.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
Disclaimer
Solutions can be stored at 2-8°C for several weeks or at -20°C for more extended periods.
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Ta pozycja | |||
|---|---|---|---|
| description powder, BioReagent, suitable for cell culture | description potency: ≥603 μg per mg | description powder, γ-irradiated | description VETRANAL®, analytical standard |
| antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria |
| mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action protein synthesis | interferes |
| technique(s) cell culture | mammalian: suitable, cell culture | plant: suitable | technique(s) - | technique(s) - | technique(s) HPLC: suitable, gas chromatography (GC): suitable |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| product line BioReagent | product line - | product line - | product line VETRANAL® |
| form powder | form powder | form powder | form - |
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Słowo ostrzegawcze
Warning
Kody zagrożeń
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Narządy docelowe
Respiratory system
Klasa składowania
11 - Combustible Solids
Co się dzieje?
WGK 2
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
PPE (środki ochrony indywidualnej)
Eyeshields, Gloves, type N95 (US)
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