S5375

Shikimic acid

≥99%, suitable for ligand binding assays

• Synonim(y): (3R,4S,5R)-(−)-3,4,5-Trihydroxy-1-cyclohexenecarboxylic acid
• Wzór empiryczny (zapis Hilla): C₇H₁₀O₅
• Numer CAS: 138-59-0
• Masa cząsteczkowa: 174.15
• NACRES: NA.25
• PubChem Substance ID: 24899647
• UNSPSC Code: 12352106
• EC Number: 205-334-2
• MDL number: MFCD00066278
• Beilstein/REAXYS Number: 2210055

Właściwości

• Nazwa produktu: Shikimic acid, ≥99%
• Quality Segment: 200
• assay: ≥99%
• form: powder
• technique(s): ligand binding assay: suitable
• color: white to off-white
• mp: 185-187 °C (lit.)
• SMILES string: O[C@@H]1CC(=C[C@@H](O)[C@H]1O)C(O)=O
• InChI: 1S/C7H10O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1,4-6,8-10H,2H2,(H,11,12)/t4-,5-,6-/m1/s1
• InChI key: JXOHGGNKMLTUBP-HSUXUTPPSA-N

Opis

Application

Shikimic acid has been used as a standard for the quantification of shikimate in apical parts of roots. It has also been used as a substrate in shikimate kinase assay.

Biochem/physiol Actions

Shikimic acid is observed to be carcinogenic in rat models, when administered. It serves as a precursor for the biosynthesis of aromatic amino acids, alkaloids and other aromatic metabolites in microorganisms. Shikimic acid is known to inhibit adenosine diphosphate (ADP) induced platelet aggregation and blood coagulation in rabbits.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS05
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H318
• Ostrzeżenia: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• PPE (środki ochrony indywidualnej): Eyeshields, Gloves, type N95 (US)