SML0049

Polygodial

≥97% (HPLC), Transient Receptor Potential Anykrin 1 channels activator, powder

• Synonim(y): (1R,4aS,8aS)-1,4,4a,5,6,7,8,8a-Octahydro-5,5,8a-trimethyl-1,2-naphthalenedicarboxaldehyde
• Wzór empiryczny (zapis Hilla): C₁₅H₂₂O₂
• Numer CAS: 6754-20-7
• Masa cząsteczkowa: 234.33
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥97% (HPLC)
• Form: powder

Właściwości

• Nazwa produktu: Polygodial, ≥97% (HPLC)
• Quality Segment: 100
• assay: ≥97% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: −20°C
• SMILES string: O=C[C@@H]1[C@@]2([C@H](C(CCC2)(C)C)CC=C1C=O)C
• InChI: 1S/C15H22O2/c1-14(2)7-4-8-15(3)12(10-17)11(9-16)5-6-13(14)15/h5,9-10,12-13H,4,6-8H2,1-3H3/t12-,13-,15+/m0/s1
• InChI key: AZJUJOFIHHNCSV-KCQAQPDRSA-N

Opis

Biochem/physiol Actions

Polygodial is a TRPA1 activator; antifungal.

Polygodial is a selective activator of Transient Receptor Potential Anykrin 1 (TRPA1) channels. Initially painful, polygodial acts as an analgesic by desensitizing sensory neuron. Polygodial also has broad antifungal properties, and is cytotoxic against bacteria and algae.

Polygodial is a sesquiterpene dialdehyde. It is obtained from the plants Polygonum hydropiper, Warburgia ugandensis, Pseudowintera colorata and Warburgia stuhlmannii. It exhibits antifeedant activity and antimicrobial activity against insects and microbes, respectively. It is responsible for the “hot taste” in peppery spices of traditional Japanese cuisine.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable