SML0285

Pleuromutilin

≥95%

• Synonim(y): Drosophilin B, Mutilin 14-glycolate, NSC 121145
• Wzór empiryczny (zapis Hilla): C₂₂H₃₄O₅
• Numer CAS: 125-65-5
• Masa cząsteczkowa: 378.50
• PubChem Substance ID: 329825293
• UNSPSC Code: 12352200
• NACRES: NA.77
• EC Number: 204-747-5
• Assay: ≥95%
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥95%
• form: powder
• optical activity: [α]/D +30 to +40° (c=1; CH2Cl2)
• color: white to beige
• solubility: DMSO: >10 mg/mL (warmed)
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@]1(C)[C@@H](C[C@@](C)(C=C)[C@@H](O)[C@@H]3C)OC(=O)CO
• InChI: 1S/C22H34O5/c1-6-20(4)11-16(27-17(25)12-23)21(5)13(2)7-9-22(14(3)19(20)26)10-8-15(24)18(21)22/h6,13-14,16,18-19,23,26H,1,7-12H2,2-5H3/t13-,14+,16-,18+,19+,20-,21+,22+/m1/s1
• InChI key: ZRZNJUXESFHSIO-BKUNHTPHSA-N

Opis

Biochem/physiol Actions

Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase center and inhibiting peptide bond formation.

Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis.

Pleuromutilin is a diterpene that acts against gram positive bacteria and mycoplasm. It is present in Pleurotus mutilus and Pleurotus passecherianus. Pleuromutilin exhibits its antibacterial action by interfering with the prokaryotic 70S ribosomal subunit and inactivates initiation complex. Pleuromutilin is useful in treating mycoplasma infections in animals.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07,GHS09
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H302,H410
• Ostrzeżenia: P264 - P270 - P273 - P301 + P312 - P391 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable