SML0378

Ralfinamide mesylate

≥98% (HPLC)

• Synonim(y): (2S)-2-[[[4-[(2-Fluorophenyl)methoxy]phenyl]methyl]amino]-propanamide methanesulfonate
• Wzór empiryczny (zapis Hilla): C₁₇H₁₉FN₂O₂ · CH₃SO₃H
• Numer CAS: 202825-45-4
• Masa cząsteczkowa: 398.45
• NACRES: NA.77
• PubChem Substance ID: 329825378
• UNSPSC Code: 12352200
• MDL number: MFCD19690932
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D 10 to 15° (c=1 HOAc)
• color: white to beige
• solubility: H₂O: >15 mg/mL
• storage temp.: 2-8°C
• SMILES string: CS(O)(=O)=O.C[C@H](NCc1ccc(OCc2ccccc2F)cc1)C(N)=O
• InChI: 1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-6-8-15(9-7-13)22-11-14-4-2-3-5-16(14)18;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1
• InChI key: CHQVNINIGBRKGZ-YDALLXLXSA-N

Opis

Biochem/physiol Actions

Ralfinamide is a mixed sodium and N-type calcium channel blocker.

Ralfinamide is a mixed sodium and N-type calcium channel blocker. Inhibiton is voltage-dependent, with higher potency against inactivated channels. Ralfinamide is two fold selective for tetrodotoxin (TTX)-resistant sodium channels compared with TTX-sensitive currents.

Features and Benefits

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H301
• Ostrzeżenia: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable