SML0465

Symadex

≥98% (HPLC)

• Synonim(y): 5-[[2-(Diethylamino)ethyl]amino]-8-hydroxy-6H-Imidazo[4,5,1-de]acridin-6-one, C-1311, C1311
• Wzór empiryczny (zapis Hilla): C₂₀H₂₂N₄O₂
• Numer CAS: 138154-39-9
• Masa cząsteczkowa: 350.41
• NACRES: NA.77
• PubChem Substance ID: 329824743
• UNSPSC Code: 12352200
• MDL number: MFCD00947296
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL (clear solution; warmed)
• storage temp.: 2-8°C
• SMILES string: CCN(CC)CCNc1ccc2ncn3-c4ccc(O)cc4C(=O)c1c23
• InChI: 1S/C20H22N4O2/c1-3-23(4-2)10-9-21-15-6-7-16-19-18(15)20(26)14-11-13(25)5-8-17(14)24(19)12-22-16/h5-8,11-12,21,25H,3-4,9-10H2,1-2H3
• InChI key: CUNDRHORZHFPLY-UHFFFAOYSA-N
• Gene Information: human ... FLT3(2322), TOP2A(7153), TOP2B(7155)

Opis

Biochem/physiol Actions

Symadex is a FLT3 and topoisomerase-II inhibitor; ABCG2 substrate; cell cycle modulator.

Symadex is an FMS-like tyrosine kinase 3 (FLT3) and topoisomerase-II inhibitor; ABCG2 substrate; cell cycle modulator.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H302
• Ostrzeżenia: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable