SML0500

GSK334429 hydrochloride

≥98% (HPLC)

• Synonim(y): 1-(1-Methylethyl)-4-((1-(6-(trifluoromethyl)-3-pyridinyl)-4-piperidinyl)carbonyl)hexahydro-1H-1,4-diazepine hydrochloride
• Wzór empiryczny (zapis Hilla): C₂₀H₂₉F₃N₄O · xHCl
• Numer CAS: 799558-94-4
• Masa cząsteczkowa: 398.47 (free base basis)
• NACRES: NA.77
• PubChem Substance ID: 329825449
• UNSPSC Code: 12352200
• MDL number: MFCD22666404
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 5 mg/mL (clear solution)
• storage temp.: 2-8°C
• SMILES string: Cl.CC(C)N1CCCN(CC1)C(=O)C2CCN(CC2)c3ccc(nc3)C(F)(F)F
• InChI: 1S/C20H29F3N4O.ClH/c1-15(2)25-8-3-9-27(13-12-25)19(28)16-6-10-26(11-7-16)17-4-5-18(24-14-17)20(21,22)23;/h4-5,14-16H,3,6-13H2,1-2H3;1H
• InChI key: RCZVWLOXPFGZDD-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

GSK334429 is a selective histamine H3 receptor antagonist.

GSK334429 is a selective histamine H3 receptor antagonist. H3 antagonists increase the release of brain histamine, ACh, NE and DA neurotransmitters that modulate cognitive processes. Studies look at their analgesic efffects including efficacy for neuropathic pain.

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

Store desiccated; dry room.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable