SML0563

Docosahexaenoyl ethanolamide

≥98% (HPLC), ethanol solution (5 mg/ml)

• Synonim(y): (4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-Hydroxyethyl)docosa-4,7,10,13,16,19-hexaenamide, DEA, DHEA, N-(2-Hydroxyethyl)-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenamide, N-Docosahexaenoylethanolamide
• Wzór empiryczny (zapis Hilla): C₂₄H₃₇NO₂
• Numer CAS: 162758-94-3
• Masa cząsteczkowa: 371.56
• NACRES: NA.77
• UNSPSC Code: 12352211
• Assay: ≥98% (HPLC)
• Form: ethanol solution (5 mg/ml)

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: ethanol solution (5 mg/ml)
• drug control: regulated under CDSA - not available from Sigma-Aldrich Canada
• color: colorless to yellow
• shipped in: dry ice
• storage temp.: −20°C

Opis

Biochem/physiol Actions

Docosahexaenoyl ethanolamide (DHEA) is a lipid signaling molecule present in brain and retina at concentrations, similar to those for arachidonoyl ethanolamide. DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM. It exhibits anti-inflammatory and organ protective activity. Studies show that docosahexaenoyl ethanolamide is the mediator of neurite growth and synaptogenesis in hippocampal neurons, resulting in enhanced synaptic activity.

Docosahexaenoyl ethanolamide (DHEA), a lipid signaling molecule, binds to the rat brain CB1 receptor and exhibits anti-inflammatory and organ protective activity.

Docosahexaenoyl ethanolamide (DHEA) has the ability to block the proliferation of head and neck squamous cell carcinoma (HNSCC) cell.

Features and Benefits

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02,GHS07
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H225,H319
• Ostrzeżenia: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2
• Klasa składowania: 3 - Flammable liquids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): 55.4 °F
• Temperatura zapłonu (°C): 13 °C