SML1070

SR-58611A

≥98% (HPLC)

• Synonim(y): Amibegron, [[(7S)-7-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydro-2-naphthalenyl]oxy acetic acid ethyl ester hydrochloride
• Wzór empiryczny (zapis Hilla): C₂₂H₂₆ClNO₄ · HCl
• Numer CAS: 121524-09-2
• Masa cząsteczkowa: 440.36
• NACRES: NA.77
• PubChem Substance ID: 329825649
• UNSPSC Code: 12352200
• MDL number: MFCD00886563
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D -75 to -95°, c = 0.5 in methanol
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: −20°C
• SMILES string: ClC1=CC([C@@H](O)CN[C@@H]2CC(C=C(OCC(OCC)=O)C=C3)=C3CC2)=CC=C1.Cl
• InChI: 1S/C22H26ClNO4.ClH/c1-2-27-22(26)14-28-20-9-7-15-6-8-19(11-17(15)12-20)24-13-21(25)16-4-3-5-18(23)10-16;/h3-5,7,9-10,12,19,21,24-25H,2,6,8,11,13-14H2,1H3;1H/t19-,21-;/m0./s1
• InChI key: NQIZCDQCNYCVAS-RQBPZYBGSA-N
• Gene Information: human ... ADRB3(155)

Opis

Biochem/physiol Actions

SR58611A is a potent, specific 3β adrenergic receptor agonist.

SR58611A is a potent, specific b3 adrenergic receptor agonist. The EC₅₀ for reduction of β3-mediated spontaneous motility in rat distal colon sections is 3.5 nM. Minimal anti-depressant efficacious doses for SR58611A are 0.1-0.3 mpk in rodent models.

Features and Benefits

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS09
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H410
• Ostrzeżenia: P273 - P391 - P501
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable