SML1804

AM4113

≥98% (HPLC)

• Synonim(y): 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
• Wzór empiryczny (zapis Hilla): C₁₇H₁₂Cl₃N₃O
• Numer CAS: 614726-85-1
• Masa cząsteczkowa: 380.66
• UNSPSC Code: 12352200
• PubChem Substance ID: 329826077
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to brown
• solubility: DMSO: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: ClC1=CC(Cl)=C(N2C(C3=CC=C(Cl)C=C3)=C(C)C(C(N)=O)=N2)C=C1
• InChI key: BBUKVPCUOHFAQN-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

AM4113 is a Cannabinoid CB-1 neutral antagonist.

AM4113 is a Cannabinoid CB-1 neutral antagonist. AM4113 reduced reward and reinstatement of drug-seeking behavior, reducing cue-induced reinstatement in monkeys trained to self-administer cocaine.

AM4113 is a pyrazole-3-carboxamide analog of rimonabant (SR141716A). In rats, it suppresses food-motivated behaviors and food intake, thereby reducing weight gain without inducing nausea. AM4113 has poor oral bioavailability. Therefore, it may not act as an effective appetite suppressant in humans.

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Informacja o środkach bezpieczeństwa

• Kody zagrożeń: H413
• Ostrzeżenia: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable