Kluczowe dokumenty

Wyświetl całą dokumentację

Przejdź do

T8938

Active Native Bovine Thyroid Stimulating Hormone

Name: Active Native Bovine Thyroid Stimulating Hormone
Brand: SIGMA

Lyophilized powder, ≥ 25IU/mg protein

Synonim(y):

TSH, Thyroid stimulating hormone, Thyrotropin from bovine pituitary glands

Zaloguj się, aby wyświetlić ceny organizacyjne i kontraktowe.

Wybierz wielkość

Zmień widok

Rozmiar/SKU	Dostępność	Cena netto

Informacje o tej pozycji

UNSPSC Code:

51111800

Biological source:

bovine pituitary glands

Form:

lyophilized powder

Informacje o cenach i dostępności nie są obecnie dostępne.

Pomoc techniczna

Potrzebujesz pomocy? Nasz zespół doświadczonych naukowców chętnie Ci pomoże.

Pozwól nam pomóc

Właściwości

biological source

bovine pituitary glands

Quality Segment

100

form

lyophilized powder

mol wt

(α subunit ≈ 13–15 kDa
β subunit ≈ 15–17 kDa
Total ≈ 28–32 kDa)

purified by

chromatography

suitability

suitable for molecular biology

UniProt accession no.

P01223, P16473

shipped in

wet ice

storage temp.

-10 to -25°C

target post-translational modification

disulfide bond

Gene Information

bovine ... CGA(280749), TSHB(281552)

Opis

General description

TSH is a heterodimeric glycoprotein hormone secreted by the anterior pituitary gland. It consists of a common α-subunit shared with other glycoprotein hormones (FSH, LH, and hCG) and a hormone-specific β-subunit that confers receptor specificity. Native bovine TSH is structurally conserved across mammalian species and exhibits biological activity through interaction with the thyroid-stimulating hormone receptor (TSHR). As a glycosylated protein, its biological activity and stability are influenced by its carbohydrate moieties.

Application

Thyroid stimulating hormone has been used in:

Studies of thyroid function and regulation
Cell-based assays involving TSH receptor activation
Endocrine signaling and hormone response studies
Assays evaluating thyroid hormone biosynthesis

Biochem/physiol Actions

TSH binds to the TSH receptor (TSHR) on thyroid follicular cells, activating cAMP-dependent signaling pathways that regulate thyroid hormone synthesis and secretion (T3 and T4). It plays a central role in maintaining metabolic homeostasis and regulating growth and development.

Physical form

Lyophilized from 10mM KPB (pH 8.0), 0.150M NaCl

Preparation Note

It is recommended that the powder be reconstituted in physiological saline (PH7.0)

Ta strona może zawierać tekst przetłumaczony maszynowo.

Porównaj podobne pozycje

Wyświetl pełne porównanie

Pokaż różnice

1 of 1

Ta pozycja	T8931	RAB0502	T9265
T8938 Active Native Bovine Thyroid Stimulating Hormone	Sigma-Aldrich T8931 Thyrotropic hormone from bovine pituitary	Sigma-Aldrich RAB0502 Human Thyroid Stimulating Hormone ELISA Kit	Sigma-Aldrich T9265 Thyrotropic hormone from human pituitary
description Lyophilized powder, ≥ 25IU/mg protein	description -	description for serum, plasma, cell culture supernatants and urine	description lyophilized powder, ≥6.2 IU/mg (immunoassay, non-sterile)
biological source bovine pituitary glands	biological source bovine pituitary glands	biological source -	biological source human pituitary glands
Quality Level 100	Quality Level 200	Quality Level -	Quality Level 200
form lyophilized powder	form powder	form -	form lyophilized powder
Gene Information bovine ... CGA(280749), TSHB(281552)	Gene Information cow ... TSHB(281552) human ... TSHR(7253)	Gene Information human ... CGA(1081), TSHB(7252)	Gene Information human ... TSHB(7252), TSHR(7253)
storage temp. -10 to -25°C	storage temp. 2-8°C	storage temp. −20°C	storage temp. 2-8°C
shipped in wet ice	shipped in -	shipped in wet ice	shipped in ambient

Klasa składowania

11 - Combustible Solids

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Dokumenty section.

Proszę o kontakt, jeśli potrzebna jest pomoc Obsługa Klienta

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów