T9778

Tropicamide

Muscarinic receptor antagonist, solid

• Synonim(y): N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide, Ro 1-7683
• Wzór empiryczny (zapis Hilla): C₁₇H₂₀N₂O₂
• Numer CAS: 1508-75-4
• Masa cząsteczkowa: 284.35
• NACRES: NA.77
• PubChem Substance ID: 24277879
• UNSPSC Code: 12352200
• EC Number: 216-140-2
• MDL number: MFCD00058580
• Form: solid

Właściwości

• Nazwa produktu: Tropicamide, solid
• form: solid
• Quality Segment: 100
• color: white
• solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.3 mg/mL, ethanol: 5.6 mg/mL, H₂O: insoluble
• storage temp.: 2-8°C
• SMILES string: CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2
• InChI: 1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3
• InChI key: BGDKAVGWHJFAGW-UHFFFAOYSA-N
• Gene Information: human ... CHRM3(1131), CHRM4(1132)

Opis

Application

Tropicamide has been used for studying the regulation of fragile X behavior in male mice. 1% tropicamide has also been used for dilating mice pupils.

Biochem/physiol Actions

M₄ muscarinic acetylcholine receptor antagonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

Tropicamide is soluble in 45% (w/v) aqueous 2-hydroxypropyl-beta-cyclodextrin (4.3 mg/mL) and ethanol (5.6 mg/mL).

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H302 + H312 + H332,H315,H317,H319,H335
• Ostrzeżenia: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Narządy docelowe: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable