UC175

(S)-(+)-Mephenytoin

≥98% (HPLC), solid, CYP2B6 & CYP2C19 substrate

• Synonim(y): (S)-(+)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione, (S)-(+)-5-Ethyl-3-methyl-5-phenylhydantoin
• Wzór empiryczny (zapis Hilla): C₁₂H₁₄N₂O₂
• Numer CAS: 70989-04-7
• Masa cząsteczkowa: 218.25
• UNSPSC Code: 12161501
• PubChem Substance ID: 24724646
• NACRES: NA.77
• MDL number: MFCD00270025
• Assay: ≥98% (HPLC)
• Form: solid

Właściwości

• Nazwa produktu: (S)-(+)-Mephenytoin, solid, ≥98% (HPLC)
• Quality Segment: 200
• assay: ≥98% (HPLC)
• form: solid
• color: off-white
• mp: 135-138 °C
• solubility: DMSO: soluble
• storage temp.: 2-8°C
• SMILES string: CC[C@]1(NC(=O)N(C)C1=O)c2ccccc2
• InChI: 1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)/t12-/m0/s1
• InChI key: GMHKMTDVRCWUDX-LBPRGKRZSA-N

Opis

Application

S-Mephenytoin has been used as a CYP2C19 substrate for the analysis of cytochrome P450 metabolism. S-Mephenytoin has also been used as probe substrates for LC/MS-based analysis of relative activity factor (RAF).

Biochem/physiol Actions

CYP2B6 & CYP2C19 substrate. Methenytoin isomer. Anticonvulsant; antiepileptic.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

(S)-(+)-Mephenytoin is soluble in DMSO.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H302,H315,H319,H335
• Ostrzeżenia: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Narządy docelowe: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): dust mask type N95 (US), Eyeshields, Gloves