Z0153

ZM 241385

≥98% (HPLC), adenosine A2A antagonist, powder

• Synonim(y): 4-(-2-[7-amino-2-{2-furyl}{1,2,4}triazolo{2,3-a} {1,3,5}triazin-5-yl-amino]ethyl)phenol
• Wzór empiryczny (zapis Hilla): C₁₆H₁₅N₇O₂
• Numer CAS: 139180-30-6
• Masa cząsteczkowa: 337.34
• UNSPSC Code: 12352200
• PubChem Substance ID: 329831597
• NACRES: NA.77
• MDL number: MFCD00908394
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Nazwa produktu: ZM 241385, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: DMSO: >15 mg/mL
• storage temp.: room temp
• SMILES string: Nc1nc(NCCc2ccc(O)cc2)nc3nc(nn13)-c4ccco4
• InChI: 1S/C16H15N7O2/c17-14-20-15(18-8-7-10-3-5-11(24)6-4-10)21-16-19-13(22-23(14)16)12-2-1-9-25-12/h1-6,9,24H,7-8H2,(H3,17,18,19,20,21,22)
• InChI key: PWTBZOIUWZOPFT-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

ZM 241385 is a potent selective adenosine A2A antagonist.

ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders.

Features and Benefits

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable