1102929

Cetirizine dihydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonim(y): [2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride
• Wzór empiryczny (zapis Hilla): C₂₁H₂₅ClN₂O₃ · 2HCl
• Numer CAS: 83881-52-1
• Masa cząsteczkowa: 461.81
• NACRES: NA.24
• PubChem Substance ID: 329749288
• UNSPSC Code: 41116107
• MDL number: MFCD00941428

Właściwości

• grade: pharmaceutical primary standard
• agency: USP
• API family: cetirizine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: room temp
• SMILES string: OC(COCCN1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1)=O.[H]Cl.[H]Cl
• InChI: 1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H
• InChI key: PGLIUCLTXOYQMV-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Opis

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cetirizine dihydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Cetirizine Hydrochloride
• Levocetirizine Dihydrochloride

Biochem/physiol Actions

Cetirizine hydrochloride is a non-sedating type histamine H1-receptor antagonist.

Cetirizine hydrochloride is an orally active and selective H1-receptor antagonist. Antihistaminic; Piperazines. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable