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Occupational contact dermatitis in painters: an analysis of patch test data from the Danish Contact Dermatitis Group.

Contact dermatitis (2012-05-04)
Anja P Mose, Michael D Lundov, Claus Zachariae, Torkil Menné, Niels K Veien, Grete Laurberg, Knud Kaaber, Christian Avnstorp, Klaus E Andersen, Evy Paulsen, Charlotte G Mørtz, Mette Sommerlund, Anne Danielsen, Jens Thormann, Ove Kristensen, Berit Kristensen, Bo L Andersen, Susanne Vissing, Niels H Nielsen, Jeanne D Johansen
ABSTRAKT

Painters are among the occupational groups that most commonly experience occupational contact dermatitis, but few investigations exist concerning this occupation. To characterize painters with contact dermatitis and identify the most common allergens associated with the occupation. Materials and methods. All patch test results of 219 painters and 1095 matched controls registered by the Danish Contact Dermatitis Group between 2001 and 2010 were analysed. Hand eczema (p < 0.0001) and occupational contact dermatitis (p < 0.0001) were observed significantly more often in the painters than in the group of controls. Sensitizations to the following allergens from the European baseline series were associated with the occupation and were statistically significant: methylchloroisothiazolinone/methylisothiazolinone, epoxy resin, formaldehyde, and quaternium-15. Three different isothiazolinones emerged as the most frequent sensitizers of the allergens tested in addition to the baseline series. The results indicate that painters have an increased risk of developing occupational hand eczema. Isothiazolinones and epoxy resin proved to be the two most frequent sensitizers in painters.

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Sigma-Aldrich
Hexamethylenetetramine, meets analytical specification of Ph. Eur., BP, 99-100.5% (calc. to the dried substance)
Sigma-Aldrich
2-Methyl-4-isothiazolin-3-one hydrochloride, ≥99%
Supelco
2-Methyl-4-isothiazolin-3-one, analytical standard
Methenamine, European Pharmacopoeia (EP) Reference Standard
Sigma-Aldrich
Hexamethylenetetramine, ACS reagent, ≥99.0%
Sigma-Aldrich
Hexamethylenetetramine, ReagentPlus®, 99%
Sigma-Aldrich
Hexamethylenetetramine, puriss. p.a., reag. Ph. Eur., ≥99.5% (calc. to the dried substance)
Sigma-Aldrich
2-Methyl-4-isothiazolin-3-one, 95%