Skip to Content
Merck

C4024

Carbamazepine

≥98% (HPLC), powder, sodium channel inhibitor

Synonym(s):

5H-Dibenz[b,f]azepine-5-carboxamide

Slide 1 of 5
Sign In to View Organizational & Contract Pricing.

Select a Size

1 G

460,00 kr

5 G

1 140,00 kr

10 G

1 970,00 kr

25 G

3 930,00 kr

460,00 kr

Please contact Customer Service for Availability
Request a Bulk Order

About This Item

Empirical Formula (Hill Notation):
C15H12N2O
CAS Number:
298-46-4
Molecular Weight:
236.27
UNSPSC Code:
12352200
eCl@ss:
34051404
PubChem Substance ID:
57654002
NACRES:
NA.77
EC Number:
206-062-7
MDL number:
MFCD00005073

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Carbamazepine, powder

SMILES string

NC(=O)N1c2ccccc2C=Cc3ccccc13

InChI

1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)

InChI key

FFGPTBGBLSHEPO-UHFFFAOYSA-N

form

powder

mp

191-192 °C (lit.)

solubility

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 29 mg/mL
H2O: insoluble
ethanol: soluble
propylene glycol: soluble

originator

Novartis

storage temp.

2-8°C

Quality Level

100

Gene Information

human ... BZRAP1(9256), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), PRNP(5621), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)
rat ... Scn2a1(24766), Scnn1a(25122), Scnn1g(24768), Slc6a1(79212)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
94496BP974C8981
Carbamazepine powder

Sigma-Aldrich

C4024

Carbamazepine

Carbamazepine analytical standard

Supelco

94496

Carbamazepine

Carbamazepine British Pharmacopoeia (BP) Reference Standard

BP974

Carbamazepine

Carbamazepine meets USP testing specifications

Sigma-Aldrich

C8981

Carbamazepine

form

powder

form

-

form

solid

form

solid

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

200

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 29 mg/mL, ethanol: soluble, H2O: insoluble, propylene glycol: soluble

solubility

-

solubility

-

solubility

-

originator

Novartis

originator

-

originator

-

originator

-

mp

191-192 °C (lit.)

mp

191-192 °C (lit.)

mp

191-192 °C (lit.)

mp

191-192 °C (lit.)

Application

Carbamazepine has been used to investigate its behavior in wastewater treatment and during groundwater infiltration.[1] It has also been used to find out its effects on spontaneous seizures in rats.[2]

Biochem/physiol Actions

Anticonvulsant; ligand for the GABAA receptor benzodiazepine modulatory site. Sodium channel inhibitor.
Carbamazepine is considered as a safe antiepileptic drug. It decreases the multiple drug therapy and maintains a better control of epilepsy.[3]

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1A - Resp. Sens. 1 - Skin Sens. 1A - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCZ4253
MKCW3471
MKCT1147
MKCS8041
MKCT3831

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Carbamazepine as a possible anthropogenic marker in the aquatic environment: investigations on the behaviour of carbamazepine in wastewater treatment and during groundwater infiltration
Clara M, et al.
Water Research, 38(4), 947-954 (2004)
Role of carbamazepine in reducing polypharmacy in epilepsy
Maheshwari MC and Padmini R
Acta Neurologica Scandinavica, 64(1), 22-28 (1981)
Opeyemi Samson Osuntokun et al.
Toxicology reports, 7, 1592-1596 (2020-12-12)
This study investigated the effects of co-administration of carbamazepine (CBZ) with grape (Vitis vinifera) seed methanolic extract (GSME) on liver toxicity. Thirty-five male rats (145-155 g) were randomized into 5 groups (n = 7) and administered with propylene glycol (PG
K Ogawa et al.
European journal of pain (London, England), 16(7), 994-1004 (2012-02-18)
Lysophosphatidic acid (LPA), an initiator of neuropathic pain, causes allodynia. However, few studies have evaluated the pharmacological profile of LPA-induced pain. In this study, a LPA-induced pain model was developed and pharmacologically characterized with clinically relevant drugs used for neuropathic
Effect of antiepileptic drugs on spontaneous seizures in epileptic rats
Nissinen J and Pitkanen A
Epilepsy Research, 73(2), 181-191 (2007)
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service