If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
R5010
Resveratrol
≥99% (HPLC)
Synonym(s):
3,4′,5-Trihydroxy-trans-stilbene, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol
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2 650,00 kr
6 510,00 kr
About This Item
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Product Name
Resveratrol, ≥99% (HPLC)
InChI
1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
SMILES string
Oc1ccc(cc1)\C=C\c2cc(O)cc(O)c2
InChI key
LUKBXSAWLPMMSZ-OWOJBTEDSA-N
biological source
plant root (bushy knotweed)
assay
≥99% (HPLC)
form
powder
solubility
acetone: 50 mg/mL, clear, faintly yellow
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
Quality Level
Gene Information
human ... AR(367), CYP1A2(1544), ESR1(2099), SIRT1(23411)
mouse ... Nos2(18126)
rat ... Esr1(24890)
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Related Categories
1 of 4
This Item | 76511 | PHR2201 | PHL89539 |
|---|---|---|---|
| biological source plant root (bushy knotweed) | biological source - | biological source - | biological source - |
| form powder | form - | form - | form - |
| assay ≥99% (HPLC) | assay - | assay - | assay ≥95.0% (HPLC) |
| Quality Level 200 | Quality Level 300 | Quality Level 300 | Quality Level - |
| application(s) metabolomics | application(s) food and beverages | application(s) pharmaceutical small molecule | application(s) food and beverages |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
Application
- in entrapment experiment[1]
- to study its neuroprotective effect on retinal neuronal cell death mediated by diabetes-induced activation of Ca2+/calmodulin-dependent protein kinase II[2]
- as a standard in the assessment of stilbene content in grapevine leaf by in vivo fluorometry[3]
Biochem/physiol Actions
Preparation Note
related product
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
>392.0 °F - closed cup - (External MSDS)
flash_point_c
> 200.0 °C - closed cup - (External MSDS)
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Articles
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
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How can I determine the shelf life / expiration / retest date of this product?
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Can a resveratrol solution turn red?
1 answer-
Solubility is tested in acetone, resulting in a faint yellow color. In acidic conditions, resveratrol can appear more reddish. In neutral or alkaline conditions, resveratrol will appear yellowish or colorless. Oxidation of resveratrol may also change its color, potentially leading to a reddish hue. Resveratrol is highly oxidizable and reacts readily with reactive oxygen species.
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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What is the solubility limit in ethanol ?
1 answer-
This product is tested for solubility in acetone at 50 mg/mL. It is soluble in ethanol at 50 mg/mL and in DMSO at 16 mg/mL.
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does it expires? How long does powder last?
1 answer-
This product is not assigned an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one year warranty from the date of shipment. For more information you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.
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1- What is the iso-form (Cis or Trans) of the Resveratrol product R5010-500MG? 2- Do you have it emission spectra in 2-propanol and DMSO?
1 answer-
As per the IUPAC name given, this product is a trans isoform. Unfortunately, emission spectra in 2-propanol and DMSO cannot be provided.
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Can Resveratrol, Product R5010, be used as a treatment for human patients?
1 answer-
No. Unfortunately, none of our catalog items are suitable for pharmaceutical applications. To inquire further on our ability to provide USP material please email our SAFC Pharma group at [email protected].
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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How do I dissolve Resveratrol, Product R5010?
1 answer-
We test the solubility in ethanol at a concentration of 50 mg/mL. It is also soluble at 16 mg/mL in DMSO (with sonication). It is practically insoluble in water.
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How do I store Resveratrol, Product R5010, once in solution?
1 answer-
A 5 mM solution of R5010 in ethanol has been found to be stable for 12 weeks when stored at 2-8°C and protected from light.Given a molecular weight of 228.24, a 5 mM solution is approximately 1.1 mg/mL.Reference: D.M. Goldberg, et al., J. Chrom. A, 708, 89-98 (1995).
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