SIRT1
sirtuin 1
Sinónimos:
SIR2L1
Especie:
Human SIRT1 (23411), Mouse Sirt1 (93759), Rat Sirt1 (309757), cow SIRT1 (613629), naked mole-rat Sirt1 (101720282), dog SIRT1 (489012), domestic cat SIRT1 (101087610), chicken SIRT1 (423646), Zebrafish sirt1 (797132), domestic guinea pig Sirt1 (100717014) ...Más
ID UniProtKB:
ID del gen:
- Human(23411) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
- Mouse(93759) sirtuin 1
- Rat(309757) sirtuin 1
- cow(613629) sirtuin 1
- naked mole-rat(101720282) sirtuin 1
- dog(489012) sirtuin 1
- domestic cat(101087610) sirtuin 1
- chicken(423646) sirtuin 1
- Zebrafish(797132) sirtuin (silent mating type information regulation 2 homolog) 1
- domestic guinea pig(100717014) sirtuin 1
- sheep(101102956) sirtuin 1
- Domestic Rabbit(100349271) sirtuin 1
- Horse(100072571) sirtuin 1
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Small Molecule - Activator
Número de producto
Descripción
Especie
Activity Assay
Número de producto
Descripción
Especie
Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-SIRT1, clon 10E4, clone 10-E-4, from mouse,
Reactividad de especies
human, mouse
Aplicación
ChIP
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Sirt1 Antibody, clone 3H10.2, clone 3H10.2, Upstate®, from mouse,
Reactividad de especies
human
Aplicación
immunoprecipitation (IP)
western blot
western blot
Anti- SIRT1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-Sirt1 (Sir2) Antibody, Alexa Fluor™ 488 Conjugate, from rabbit, ALEXA FLUOR™ 488,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
Anti-Phospho-SIRT1-S47 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot