CC077

人胶原V型

Name: 人胶原V型
Brand: MM
Price: 770 SGD
Availability: InStock

from human placenta, liquid, 1 mg/mL, suitable for cell culture, used for gel formation

别名:

V型胶原蛋白

Slide 1 of 1

登录查看公司和协议定价

选择尺寸

100 μG

$770.00

预计发货时间2025年12月26日详情

获取大包装/定制包装报价

关于此项目

分類程式碼代碼:

12352202

eCl@ss:

32160405

NACRES:

NA.75

主要文件

查看所有文档

跳至

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

产品名称

人胶原V型, 1 mg/mL, solution, BioReagent, suitable for cell culture

生物源

human

品質等級

200

化驗

95% (SDS-PAGE)

形狀

solution

製造商／商標名

Chemicon^®

濃度

1 mg/mL

技術

cell culture | mammalian: suitable

雜質

<0.5% non-collagen proteins
<1% collagen type III
<2% collagen type I
<2% collagen type IV

輸入

sample type mesenchymal stem cell(s)
sample type induced pluripotent stem cell(s)
sample type pancreatic stem cell(s)
sample type epithelial cells
sample type neural stem cell(s)
sample type hematopoietic stem cell(s)
sample type: human embryonic stem cell(s)

NCBI登錄號

NM_000093.3

UniProt登錄號

P20908

運輸包裝

dry ice

儲存溫度

−20°C

基因資訊

human ... COL5A1(1289), COL5A2(1290)

比较类似商品

查看完整比较结果

显示差异

1 of 4

此商品	CC052	CC076	C6745
Sigma-Aldrich CC077 人胶原V型	Sigma-Aldrich CC052 人型胶原蛋白II型	Sigma-Aldrich CC076 人IV型胶原蛋白	Sigma-Aldrich C6745 胶原蛋白IV型来源于人类细胞培养基
biological source human	biological source human	biological source human	biological source human cell culture
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
assay 95% (SDS-PAGE)	assay 90% (Human collagen type II)	assay 95% (Human collagen type IV, SDS-PAGE)	assay -
concentration 1 mg/mL	concentration 1 mg/mL	concentration 1 mg/mL	concentration 0.3 mg/mL
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 200
form liquid	form liquid	form liquid	form solution

一般說明

V型胶原是纤维型胶原蛋白，存在于肺、骨、胎膜中，与I型胶原共分布。[1]位于细胞外基质，含量偏低。[2]

應用

人类V型胶原蛋白已用于荧光偏振(FP)分析和表面等离子共振(SPR)技术研究高内皮细胞微静脉蛋白(high endothelial venule protein, hevin)和人V型胶原的相互作用。[3]还用于孵育96孔板，用于测定基质和成纤维细胞裂解物中的蛋白水平。[1]

生化／生理作用

V型胶原可调节角膜和皮肤真皮中的胶原纤维形成。与基质胶原和结构蛋白相互作用，共同维持组织的结构完整性。V型胶原水平偏低会导致角膜透明度的丧失和Ehlers-Danlos综合征（皮肤弹性过度综合征）。[2]

外觀

液体，在0.1 M醋酸（pH 3.0）中。没有添加防腐剂。

準備報告

将未稀释的分装样品保存于-20°C，最长12个月。请勿解冻和重新冷冻。

通过人胎膜胃蛋白酶提取物的连续盐沉淀和DEAE-纤维素色谱纯化。

其他說明

分子组成：α1(V)]2 α2(V),天然三螺旋。通过SDS-PAGE，ORD测量以及与抗胶原类型特异性单克隆抗体的反应来监测天然螺旋结构的纯度和保留。产品来源：人胎盘，HBsAg和HIV抗体阴性

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

仅供研究使用。在法国，在用于科研目的时（包括进口和出口活动（《公共健康法》第L 1211-1条，第2节））该产品为管制品。购买者（即最终用户）需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

输入产品批号来搜索分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Beneficial regulation of fibrillar collagens, heat shock protein-47, elastin fiber components, transforming growth factor-β1, vascular endothelial growth factor and oxidative stress effects by copper in dermal fibroblasts.

Neena Philips et al.

Connective tissue research, 53(5), 373-378 (2012-02-14)

Skin aging is associated with the loss of the structural collagens and the elastin fiber components that form the extracellular matrix (ECM). It is associated with reduced transforming growth factor-β (TGF-β), angiogenesis and increased oxidative stress. Copper has been incorporated

Type V collagen in health, disease, and fibrosis

The Anatomical Record, 299(5), 613-629 (2016)

The effects of tissue pretreatment and pepsin levels on the isolation of collagens from human placenta.

Klasson, S C, et al.

Collagen and Related Research, 6, 397-408 (1986)

Collagens--structure, function, and biosynthesis.

K Gelse et al.

Advanced drug delivery reviews, 55(12), 1531-1546 (2003-11-19)

The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions. The most abundant family is the collagens with more than 20 different collagen types identified so far. Collagens are

Interplay between hevin, SPARC, and MDGAs: Modulators of neurexin-neuroligin transsynaptic bridges.

Shanghua Fan et al.

Structure (London, England : 1993), 29(7), 664-678 (2021-02-04)

Hevin is secreted by astrocytes and its synaptogenic effects are antagonized by the related protein, SPARC. Hevin stabilizes neurexin-neuroligin transsynaptic bridges in vivo. A third protein, membrane-tethered MDGA, blocks these bridges. Here, we reveal the molecular underpinnings of a regulatory network

查看所有相关文献

实验方案

ECM Coating Protocols for Millicell®

This page covers the ECM coating protocols developed for four types of ECMs on Millicell®-CM inserts, Collagen Type 1, Fibronectin, Laminin, and Matrigel.

Questions

Reviews

No rating value

Active Filters

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持