产品名称
抗-GLUT1 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 54 kDa
species reactivity
mouse, human, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SLC2A1(6513)
1 of 4
此商品 | SAB4200519 | SAB1303865 | HPA005449 |
|---|---|---|---|
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| biological source rabbit | biological source rabbit | biological source rabbit | biological source rabbit |
| antibody form affinity isolated antibody | antibody form affinity isolated antibody | antibody form IgG fraction of antiserum | antibody form affinity isolated antibody |
| species reactivity mouse, human, rat | species reactivity mouse, rat, human | species reactivity human | species reactivity human |
| mol wt antigen 54 kDa | mol wt antigen ~55-70 kDa | mol wt 57359 Da | mol wt - |
Application
兔抗GLUT1抗体可用于:
- 蛋白提取
- 蛋白质印迹法
- 免疫组织化学
抗GLUT1,C端抗体适用于蛋白质印迹和免疫组织化学。
Biochem/physiol Actions
GLUT1是一种膜蛋白,可调节葡萄糖跨细胞的促进转运。编码GLUT1的基因中的突变与癫痫和糖尿病肾病相关。GLUT1的表达增加与乳腺癌和子宫内膜癌的肿瘤分化有关,而GLUT1功能降低会导致GLUT1缺乏综合征。抗-GLUT1,C端抗体可用于检测总GLUT1蛋白的内源水平。该抗体在小鼠、大鼠和人中与GLUT1发生特异性反应。
GLUT1(1型葡萄糖转运蛋白)充当人类T细胞白血病病毒(HTLV)I和II的受体。它在HTLV包膜介导的感染中起关键作用。GLUT1与阵发性劳累引起的运动障碍有关。Glut1可能调节脑微血管,内皮细胞的增殖和BBB(血脑屏障)的连接复合物的发育。它通过血脑屏障转运葡萄糖。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用,我们将全额退款或安排替代抗体。了解更多信息。
General description
抗-GLUT1抗体可检测总GLUT1蛋白的内源性水平。
GLUT1(1型葡萄糖转运蛋白)基因定位于人类染色体1p34.2。它在大脑内皮细胞中表达。
Immunogen
该抗血清是针对衍生自人GLUT1的合成肽而生成的。
免疫原范围: 441-490
免疫原范围: 441-490
Physical form
兔IgG,溶于磷酸盐缓冲液(不含Mg2+和Ca2+),pH 7.4,150mM NaCl,0.02%叠氮化钠和50%甘油中。
未找到合适的产品?
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Yang Li et al.
Molecular metabolism, 66, 101630-101630 (2022-11-08)
Bone is a highly dynamic organ that undergoes constant bone formation and remodeling, and glucose as a major nutrient is necessary for bone formation and remodeling. Retinoblastoma (Rb1) is a critical regulator of mesenchymal stem cells (MSCs) fate, but how
Valeria Meier et al.
PloS one, 11(2), e0149993-e0149993 (2016-02-26)
For various types of tumor therapy, it is suggested that co-targeting of tumor microenvironment, mainly tumor vasculature, mediates tumor response mechanisms. Immunohistochemistry for glucose transporter-1 (GLUT-1), carbonic anhydrase-IX (CAIX), Ki-67, and von Willebrand factor VIII for microvessel density (MVD) were
Glucose modulation induces reactive oxygen species and increases P-glycoprotein-mediated multidrug resistance to chemotherapeutics
Seebacher NA, et al.
British Journal of Pharmacology, 172(10), 2557-2572 (2015)
The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV
Manel N, et al.
Cell, 115(4), 449-459 (2003)
Paroxysmal dyskinesias
Bhatia KP
Movement Disorders, 26(6), 1157-1165 (2011)
Active Filters
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持


