MTH17MAG-47K

MILLIPLEX^® Mouse TH17 Magnetic Bead Panel - Immunology Multiplex Assay

Simultaneously analyze multiple Th17 cytokine and chemokine biomarkers with the Th17 Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.

• Synonym(s): Luminex^® Mouse Immunology Panel, Millipore Mouse Immunology Panel, Mouse Immunology Protein Multiplex Assay
• UNSPSC Code: 12161503
• eCl@ss: 32161000
• NACRES: NA.84

Properties

• Quality Level: 200
• species reactivity: mouse
• manufacturer/tradename: Milliplex^®
• assay range: linearity: 111.0%; (1:04); linearity: 113.1%; (1:08); standard curve range: 1.5-1,500 pg/mL; (IL-4); standard curve range: 10-10,000 pg/mL; (IL-17F); standard curve range: 127-130,000 pg/mL; (IL-28B); standard curve range: 15-15,000 pg/mL; (IL-1β); standard curve range: 2.4-2,500 pg/mL; (IL-22); standard curve range: 20-20,000 pg/mL; (IL-10, IL-12(p70), & IL-21); standard curve range: 3.4-3,500 pg/mL; (TNFα); standard curve range: 34-35,000 pg/mL; (GM-CSF & IL-15); standard curve range: 342-350,000 pg/mL; (IL-23); standard curve range: 39-40,000 pg/mL; (IL-13 & IL-17A); standard curve range: 4.9-5,000 pg/mL; (IL-5); standard curve range: 488-500,000 pg/mL; (TNFβ); standard curve range: 49-50,000 pg/mL; (CD40L IL-31 & MIP-3α); standard curve range: 586-600,000 pg/mL; (IL-17E/ IL-25); standard curve range: 6.9-6,000 pg/mL; (IL-2); standard curve range: 7.8-8,000 pg/mL; (IFNγ & IL-6); standard curve range: 78-80,000 pg/mL; (IL-33); standard curve range: 879-900,000 pg/mL; (IL-27)
• technique(s): multiplexing: suitable
• detection method: fluorometric (Luminex xMAP)
• shipped in: wet ice

Description

General description

The MILLIPLEX^® Mouse Th17 Bead panel enables you to focus on the therapeutic potential of the modulation of CD4 T-helper cell cytokines. Coupled with the Luminex^® xMAP^®platform in a bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of dozens of analytes simultaneously, which can dramatically improve productivity.

Panel Type: Cytokines/Chemokines

Application

• Analytes: CD40 Ligand, GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12 (p70), IL-13, IL-15, IL-17A, IL-17E/IL-25, IL-17F, IL-21, IL-22, IL-23, IL-27, IL-28B, IL-31, IL-33, MIP-3α/CCL20, TNF-α, TNFβ
• Recommended Sample type: serum, plasma or tissue/cell lysate and culture supernatant
• Recommended Sample dilution: neat
• Assay Run Time: overnight or one day
• Research Category: Inflammation & Immunology

Biochem/physiol Actions

Cross Reactivty
There was no or minimum cross-reactivity between the antibodies and any other analytes in the panel (see details in assay protocol).

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

Preparation Note

Recommended storage for kit components is 2 - 8°C.

Other Notes

Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.

Legal Information

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Pictograms: GHS08,GHS05,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H302 + H312 + H332,H317,H318,H373,H411
• Precautionary Statements: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• Target Organs: Respiratory Tract
• Storage Class Code: 10 - Combustible liquids