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Merck

221163

Silver(I) oxide

ReagentPlus®, 99%

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About This Item

Empirical Formula (Hill Notation):
Ag2O
CAS Number:
Molecular Weight:
231.74
EC Number:
MDL number:
UNSPSC Code:
12352303
PubChem Substance ID:
NACRES:
NA.21
Assay:
99%
Form:
powder or chunks

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Quality Level

product line

ReagentPlus®

Assay

99%

form

powder or chunks

reaction suitability

reagent type: catalyst
core: silver

SMILES string

[Ag]O[Ag]

InChI

1S/2Ag.O

InChI key

KHJDQHIZCZTCAE-UHFFFAOYSA-N

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1 of 4

This Item
226815226831216674
form

powder or chunks

form

powder, crystals or chunks

form

powder and chunks

form

powder or chunks

assay

99%

assay

99%

assay

≥99.99% trace metals basis

assay

99%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

product line

ReagentPlus®

product line

-

product line

-

product line

ReagentPlus®

reaction suitability

reagent type: catalyst
core: silver

reaction suitability

-

reaction suitability

reagent type: catalyst
core: silver

reaction suitability

reagent type: catalyst
core: silver

Application

Mediates monoprotection of symmetrical diols with alkyl halides in good to excellent yield.[1]
Silver(I) oxide may be used to mediate the following processes:
  • Selective monoalkylation of symmetric diols in the presence of alkyl halide.[2]
  • Palladium catalyzed cross-coupling of aryl- and alkenylsilanols with organic halides.[3]
  • Palladium-catalyzed reaction of aryl and alkenyl halides with terminal alkynes to form arylated or alkenylated alkynes, respectively.[4]

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Ox. Sol. 1

Storage Class Code

5.1A - Strongly oxidizing hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Highly selective silver (I) oxide mediated monoprotection of symmetrical diols
Bouzide A and Sauve G.
Tetrahedron Letters, 38(34), 5945-5948 (1997)
A New Transformation of Silanols. Palladium-Catalyzed Cross-Coupling with Organic Halides in the Presence of Silver (I) Oxide
Hirabayashi K, et al.
Organic Letters, 1(2), 299-302 (1999)
Eagleson M.
Concise Encyclopedia Chemistry, 90-90 (1994)
Non-Sonogashira-type palladium-catalyzed coupling reactions of terminal alkynes assisted by silver (I) oxide or tetrabutylammonium fluoride.
Mori A, et al.
Organic Letters, 2(19), 2935-2937 (2000)
Bouzide, A. Sauve, G.
Tetrahedron Letters, 38, 5945-5945 (1997)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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