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Merck

EHU091311

MISSION® esiRNA

targeting human PROM2

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UNSPSC Code:
41105324
NACRES:
NA.51

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description

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Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GTGGTCCTATTCGTGGTGCTCTGCAACCTGCTGGGCCTCAATCTGGGCATCTGGGGCCTGTCTGCCAGGGACGACCCCAGCCACCCAGAAGCCAAGGGCGAGGCTGGAGCCCGCTTCCTCATGGCAGGTGTGGGCCTCAGCTTCCTCTTTGCTGCACCCCTCATCCTCCTGGTGTTCGCCACCTTCCTGGTGGGTGGCAACGTGCAGACGCTGGTGTGCCAGAGCTGGGAGAACGGCGAGCTCTTTGAGTTTGCAGACACCCCAGGGAACCTGCCCCCGTCCATGAACCTGTCGCAACTTCTTGGCCTGAGGAAGAACATCAGCATCCACCAAGCCTATCAGCAGTGCAAGGAAGGGGCAGCGCTCTGGACAGTCCTGCAGCTCAACGACTCCTACGACC

Ensembl | human accession no.

ENSG00000155066

NCBI accession no.

NM_144707

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... PROM2(150696), PROM2(150696)

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MISSION® esiRNA targeting human PROM2

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MISSION® esiRNA targeting human GAREM2

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esiRNA cDNA target sequence

GTGGTCCTATTCGTGGTGCTCTGCAACCTGCTGGGCCTCAATCTGGGCATCTGGGGCCTGTCTGCCAGGGACGACCCCAGCCACCCAGAAGCCAAGGGCGAGGCTGGAGCCCGCTTCCTCATGGCAGGTGTGGGCCTCAGCTTCCTCTTTGCTGCACCCCTCATCCTCCTGGTGTTCGCCACCTTCCTGGTGGGTGGCAACGTGCAGACGCTGGTGTGCCAGAGCTGGGAGAACGGCGAGCTCTTTGAGTTTGCAGACACCCCAGGGAACCTGCCCCCGTCCATGAACCTGTCGCAACTTCTTGGCCTGAGGAAGAACATCAGCATCCACCAAGCCTATCAGCAGTGCAAGGAAGGGGCAGCGCTCTGGACAGTCCTGCAGCTCAACGACTCCTACGACC

esiRNA cDNA target sequence

AGCAGTTTCCTTGTCCTCCAAACTCACCAAAGGCTGTATGCGCTGTTCTTGAAATTGAATGTGCTCATGGTGCTGTTTTTGTGGCTGGGAGATATAATAAATACTCCAGGAATCTACCACAAACTCCTTGGATAATTGATGGAGAAAGGAAGCTGGAATCTTCAGTGGAAGAATTAATTTCAGATCATCTGTTGGCAGTATTTAAAGCAGAGAGTTTTAATTTTTCATCCTCTGGAAGAGAAGATGTAGATGTGAGAACATTAGGAAATGGAAGGCCCTTTGCAATTGAGCTGGTGAATCCTCATAGAGTACATTTCACTTCACAAGAAATTAAGGAACTTCAGCAGAAAATTAATAACTCATCTAACAAAATCCAAGTACGTGACTTGCAGCTTGTCACAAGAGAGGCAATAGGACA

esiRNA cDNA target sequence

TCCTGTTTTCGCCAGATTTCTTCTTGAATGGCAACCTAAATGCCAGTCCAAAGAGGCCCCCAATAGACTTGTTCACCCTTCATGTCCTCAACTCTGGGGAAGTTAAGTAATCAAGTTGAAGAAACACTTCCACTACTTAAAAAGGTACCTGCAAATTACTTTCACATTTGTTCAGCTATCCTAATGGGATTTTCACTTAGTAAATCTGCTACTCAGGTATCTGCTATACATATGGATTCAAAAGTGGATGATCACTTAATACGAGGGACTGAAAAAAGCAGGTTGGAACCAGCGACTCAGTTATTTCAAAACACCAAGAAAATAAGATTAGAAGACACAAATCAAGAAAACTTTACAAGGATTGAAGGGACTGGCACAGGATCTCTTTCTGGGAAAGCCTTG

esiRNA cDNA target sequence

TCTTTGCTCGAAACACTCCAGTGGGTCTCATGTTGTACAGAATAAAGCTTTACTGCTTTAGCAAGGCATTCAGAGCCTTTCAAATCCCAGTTGCTGTCTGCATCCCCTCCTGTCCTCCCTCTCCCTAAGTCCTTCCCTGCAGGCACGCACCATCTGGGGCAGGTGGTCTGCTTTTGTGTCTCTGTGTCTGTGTTTACAGTGTTTCTTCCACAGGGAATGCCCATTCTGTGAATTCCCTTTGATTCTTAAGGTGCAGCTCAGTGATCCTCTCAGATTCCGCCAGGCAGGTTTTGCCTACCTAGCCGTCTTGTAACTCTTTTGTCACAAGTCTGTTGTAGCACTTATCACATCCTGCCACCATTGGGTACTCATCGTCTCACCCATTATATCTGGATTTCTTTAAGGGCAGACTGTATTTTACACAGATTTGTACCCTCTGTGTGGCCTACC

Ensembl | human accession no.

ENSG00000155066

Ensembl | human accession no.

ENSG00000162927

Ensembl | human accession no.

ENSG00000170534

Ensembl | human accession no.

ENSG00000157833

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

Gene Information

human ... PROM2(150696), PROM2(150696)

Gene Information

human ... PUS10(150962), PUS10(150962)

Gene Information

human ... C2ORF15(150590), C2orf15(150590)

Gene Information

human ... GAREM2(150946), FAM59B(150946)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Caitlin W Brown et al.
Developmental cell, 51(5), 575-586 (2019-11-19)
Ferroptosis, regulated cell death characterized by the iron-dependent accumulation of lethal lipid reactive oxygen species, contributes to tissue homeostasis and numerous pathologies, and it may be exploited for therapy. Cells differ in their sensitivity to ferroptosis, however, and a key

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