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Merck

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A1663

Atrial Natriuretic Peptide human

≥97% (HPLC)

同義詞:

ANF 1-28, hANF

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關於此項目

經驗公式(希爾表示法):
C127H203N45O39S3
CAS 編號:
分子量::
3080.44
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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Quality Segment

assay

≥97% (HPLC)

form

powder

UniProt accession no.

storage temp.

−20°C

SMILES string

CCC(C)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(O)=O)NC(=O)C(CCSC)NC(=O)C(CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)C(CS)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(C)C)NC(=O)C(N)CO)C(=O)NCC(=O)NC(C)C(=O)NC(CCC(N)=O)C(=O)NC(CO)C(=O)NCC(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CS)C(=O)NC(CC(N)=O)C(=O)NC(CO)C(=O)NC(Cc2ccccc2)C(=O)NC(CCCNC(N)=N)C(=O)NC(Cc3ccc(O)cc3)C(O)=O

InChI

1S/C127H205N45O39S3/c1-9-64(6)99(121(209)150-52-94(182)151-65(7)100(188)155-76(34-35-91(129)179)109(197)167-85(56-174)104(192)149-53-96(184)153-78(43-62(2)3)102(190)148-54-97(185)154-89(60-212)119(207)164-82(48-92(130)180)114(202)169-86(57-175)116(204)163-81(46-67-23-14-11-15-24-67)113(201)158-73(27-18-39-143-125(135)136)107(195)166-84(122(210)211)47-68-30-32-69(178)33-31-68)172-111(199)75(29-20-41-145-127(139)140)159-115(203)83(49-98(186)187)165-110(198)77(36-42-214-8)160-105(193)71(25-16-37-141-123(131)132)152-95(183)51-146-93(181)50-147-103(191)80(45-66-21-12-10-13-22-66)162-120(208)90(61-213)171-118(206)88(59-177)170-117(205)87(58-176)168-108(196)74(28-19-40-144-126(137)138)156-106(194)72(26-17-38-142-124(133)134)157-112(200)79(44-63(4)5)161-101(189)70(128)55-173/h10-15,21-24,30-33,62-65,70-90,99,173-178,212-213H,9,16-20,25-29,34-61,128H2,1-8H3,(H2,129,179)(H2,130,180)(H,146,181)(H,147,191)(H,148,190)(H,149,192)(H,150,209)(H,151,182)(H,152,183)(H,153,184)(H,154,185)(H,155,188)(H,156,194)(H,157,200)(H,158,201)(H,159,203)(H,160,193)(H,161,189)(H,162,208)(H,163,204)(H,164,207)(H,165,198)(H,166,195)(H,167,197)(H,168,196)(H,169,202)(H,170,205)(H,171,206)(H,172,199)(H,186,187)(H,210,211)(H4,131,132,141)(H4,133,134,142)(H4,135,136,143)(H4,137,138,144)(H4,139,140,145)

InChI key

KGZJRXKGJRJKCB-UHFFFAOYSA-N

Gene Information

human ... NPPA(4878)

Application

Atrial natriuretic peptide (ANP) has been used to study its cross reactivity in melanin concentrating hormone (MCH) assay. It has also been used to study its effects in nerve fibres and nerve cell bodies.

Biochem/physiol Actions

Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure homeostasis.
Exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors.
Atrial natriuretic peptide (ANP) is a cardiac hormone, which maintains electrolyte homeostasis. It prevents adrenocorticotropic hormone (ACTH) release and arginine vasopressin secretion. ANP functions as a neurotransmitter and modulates pituitary and vegetative functions.

Other Notes

Lyophilized from 0.1% TFA in H2O

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本產品
B5900A8208
description

≥97% (HPLC)

description

≥97% (HPLC), powder

description

≥97% (HPLC)

assay

≥97% (HPLC)

assay

≥97% (HPLC)

assay

≥97% (HPLC)

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

UniProt accession no.

P01160

UniProt accession no.

P16860

UniProt accession no.

P01161

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Gene Information

human ... NPPA(4878)

Gene Information

human ... NPPB(4879)

Gene Information

rat ... Nppa(24602)


存儲類別/等級

11 - Combustible Solids

到底發生了什麼事?

WGK 3

閃點 (F)

Not applicable

閃點(°C)

Not applicable

PPE(個人防護裝備)

Eyeshields, Gloves, type N95 (US)



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Questions

  1. does it cross react with. mouse 

    1 answer
    1. Although not specifically tested, this material is expected to react with a mouse receptor, as the sequence of this human peptide is identical to the mouse counterpart.

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