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MilliporeSigma

07-374

Anti-phospho-KDR/Flk-1/VEGFR2 (Tyr1214) Antibody

Upstate®, from rabbit

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200 μG

$405.00

$405.00


Fecha estimada de envío31 de diciembre de 2025


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UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

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biological source

rabbit

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

phosphorylation (pTyr1214)

Gene Information

human ... KDR(3791)

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1 of 4

Este artículo
07-81904-89407-278
biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

clone

polyclonal

clone

polyclonal

clone

D1W, monoclonal

clone

polyclonal

species reactivity

mouse, human

species reactivity

human

species reactivity

mouse, human

species reactivity

human, mouse

antibody form

purified antibody

antibody form

affinity isolated antibody

antibody form

culture supernatant

antibody form

purified antibody

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

UniProt accession no.

P35968

UniProt accession no.

P00533

UniProt accession no.

P35968

UniProt accession no.

O43561

General description

200-230 kDa

Immunogen

(...FHpYDN...) in which pY corresponds to phosphorylated tyrosine at residue 1214 of human KDR/VEGFR2. Tyr1214 of human KDR corresponds to Tyr1212 in the mouse protein.

Application

Anti-phospho-KDR/Flk-1/VEGFR2 (Tyr1214) Antibody detects level of phospho-KDR/Flk-1/VEGFR2 (Tyr1214) & has been published & validated for use in WB.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors

Biochem/physiol Actions

phospho-KDR/VEGFR2 (Tyr1214)

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl,0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A purified

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot RIPA lysates from porcine aortic endothelial cells expressing human CSF-1R/murineVEGFR-2 chimera

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Clase de almacenamiento

10 - Combustible liquids

wgk_germany

WGK 1


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V Dayanir et al.
The Journal of biological chemistry, 276(21), 17686-17692 (2001-03-30)
Activation of vascular endothelial growth factor receptor-2 (VEGFR-2) plays a critical role in vasculogenesis and angiogenesis. However, the mechanism by which VEGFR-2 activation elicits these cellular events is not fully understood. We recently constructed a chimeric receptor containing the extracellular
Michael J Donovan et al.
European journal of cancer (Oxford, England : 1990), 45(8), 1518-1526 (2009-03-11)
To identify clinical and biometric features associated with overall survival of patients with advanced refractory non-small-cell lung cancer (NSCLC) treated with gefitinib. One hundred and nine diagnostic NSCLC samples were analysed for EGFR mutation status, EGFR immunohistochemistry, histologic morphometry and
Substitution of C-terminus of VEGFR-2 with VEGFR-1 promotes VEGFR-1 activation and endothelial cell proliferation.
Meyer, Rosana D, et al.
Oncogene, 23, 5523-5531 (2004)
Preclinical activity of ABT-869, a multitargeted receptor tyrosine kinase inhibitor.
Albert, DH; Tapang, P; Magoc, TJ; Pease, LJ; Reuter, DR; Wei, RQ; Li, J; Guo, J; Bousquet et al.
Molecular Cancer Therapeutics null
Phosphorylation of Akt and ERK1/2 is required for VEGF-A/VEGFR2-induced proliferation and migration of lymphatic endothelium.
Dellinger, MT; Brekken, RA
Testing null

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