5.31038

TAT-Beclin-1, Scrambled

≥95% (HPLC), powder, Beclin-1 activator, Calbiochem^®

• Sinónimos: Beclin-1 Activator I, TAT-Beclin-1, Scrambled, H₂N-YGRKKRRQRRR-GG-VGNDFFINHETTGFATEW-CO₂H
• Fórmula empírica (notación de Hill): C₁₆₄H₂₅₁N₅₇O₄₅
• Peso molecular: 3741.10
• UNSPSC Code: 12352200
• NACRES: NA.77

Propiedades

• Nombre del producto: Beclin-1 Activator I, TAT-Beclin-1, Scrambled,
• assay: ≥95% (HPLC)
• form: powder
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic); protect from light
• color: white
• solubility: water: 25 mg/mL
• storage temp.: 2-8°C
• Quality Level: 100

Descripción

Biochem/physiol Actions

Cell permeable: yes

Reversible: yes

Disclaimer

Toxicity: Standard Handling (A)

General description

Beclin-1 (267-284), a randomly shuffled peptideis made cell-permeable by attaching covalently to a human immunodeficiency virus(HIV)-1 Tat protein transduction domain via a diglycine linker. Beclin-1activating peptide I, TAT-Beclin-1, is observed to promote autophagy invitro and in vivo in pharmacological research.[1]

Other Notes

H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg~Gly-Gly~Val-Gly-Asn-Asp-Phe-Phe-Ile-Asn-His-Glu-Thr-Thr-Gly-Phe-Ala-Thr-Glu-Trp-OH

Liu, Y., et al. 2013. Proc. Natl. Acad. Sci. USA110, 20364.
Shoji-Kawata, S., et al. 2013. Nature.494, 201.

Packaging

Packaged under inert gas

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable