Four mouse samples were tested in the panel, and none of them showed detection. According to the capture antibody datasheet, the antibody was tested with recombinant mouse BCA-1 and exhibited no cross-reactivity.
HCYP2MAG-62K
MILLIPLEX® Human Cytokine/Chemokine Magnetic Bead Panel II - Immunology Multiplex Assay
Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.
Sinónimos:
Human cytokine multiplex kit, Luminex® human cytokine immunoassay, Millipore human cytokine panel
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UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.84
To order a Milliplex® kit, please search for your analyte of interest.
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Permítanos ayudarleQuality Level
species reactivity
human
manufacturer/tradename
Milliplex®
assay range
accuracy: 81-110%
sensitivity: 0.4-55.8 pg/mL
standard curve range: 1.0-100,000 pg/mL
technique(s)
multiplexing: suitable
detection method
fluorometric (Luminex xMAP)
shipped in
wet ice
Categorías relacionadas
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Este artículo | HCYP3MAG-63K | HCYP4MAG-64K | HCYTA-60K-PX38 |
|---|---|---|---|
| species reactivity human | species reactivity human | species reactivity human | species reactivity human |
| manufacturer/tradename Milliplex® | manufacturer/tradename Milliplex® | manufacturer/tradename Milliplex® | manufacturer/tradename Milliplex® |
| assay range accuracy: 81-110%, standard curve range: 1.0-100,000 pg/mL, sensitivity: 0.4-55.8 pg/mL | assay range accuracy: 92-106%, standard curve range: 2.0-200,000 pg/mL | assay range accuracy: 101% | assay range - |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| technique(s) multiplexing: suitable | technique(s) multiplexing: suitable | technique(s) multiplexing: suitable | technique(s) multiplexing: suitable |
| shipped in wet ice | shipped in wet ice | shipped in ambient | shipped in - |
General description
“Cytokine” is a general term used for a diverse group of soluble proteins and peptides which act as regulators under both normal and pathological conditions to modulate the functional activities of individual cells and tissues. These proteins also mediate direct interactions between cells and regulate processes taking place in the extracellular environment. The cytokine group of proteins includes lymphokines, interferons, colony stimulating factors and chemokines. Cytokine and chemokine research plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, as well as disease states such as inflammatory disease, allergic reactions, irritable bowel disease (IBD), sepsis, and cancer.
The MILLIPLEX® Human Cytokine / Chemokine Panel II enables you to focus on the therapeutic potential of cytokines as well as the modulation of cytokine expression.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Cytokines/Chemokines
The MILLIPLEX® Human Cytokine / Chemokine Panel II enables you to focus on the therapeutic potential of cytokines as well as the modulation of cytokine expression.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Cytokines/Chemokines
Application
- Analytes: 6Ckine, BCA-1, CTACK, ENA-78, Eotaxin-2, Eotaxin-3, I-309, IL-16, IL-20, IL-21, IL-23, IL-28A, IL-33, LIF, MCP-2, MCP-4, MIP-1δ, SCF, SDF-1A+β, TARC, TPO, TRAIL, TSLP
- Recommended Sample type: Serum, plasma, cell culture supernatant
- Recommended Sample dilution: neat
- Assay Run Time: Overnight or two-hour primary incubation. For best results, an overnight incubation is recommended
- Research Category: Inflammation & Immunology
- Research Subcategory: Obesity, Metabolic Disorders, Inflammation & Autoimmune Mechanisms
Biochem/physiol Actions
Cross Reactivty
There was no or negligible cross-reactivity between the antibodies and any of the other analytes in this panel.
There was no or negligible cross-reactivity between the antibodies and any of the other analytes in this panel.
Features and Benefits
Design your multiplex kit by choosing available analytes within this panel.
Packaging
96 well plate
Preparation Note
Recommended storage for kit components is 2 - 8°C.
Other Notes
Please contact Technical Service for linearity of dilution.
Legal Information
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
target_organs
Respiratory Tract
Clase de almacenamiento
10 - Combustible liquids
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Cecilia K Andersson et al.
The Journal of allergy and clinical immunology, 139(6), 1819-1829 (2016-10-18)
Neutrophils and IL-17A have been linked mechanistically in models of allergic airways disease and have been associated with asthma severity. However, their role in pediatric asthma is unknown. We sought to investigate the role of neutrophils and the IL-17A pathway
Fawaz Y Azizieh et al.
Journal of inflammation research, 12, 99-108 (2019-05-24)
Objective: In addition to some well-characterized bone turnover markers (BTMs), cytokines and adipokines have also been suggested to be linked to osteoporosis seen in menopause. However, there is much controversy on the possible association between these markers and bone mineral density
Evidence of enhanced systemic inflammation in stable kidney transplant recipients with low Framingham risk scores.
Mansell, H; Rosaasen, N; Dean, J; Shoker, A
Clinical Transplantation null
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medRxiv : the preprint server for health sciences (2021-03-25)
We analyzed the plasma levels of interferons and cytokines, and the expression of interferon-stimulated genes in peripheral blood mononuclear cells in COVID-19 patients with different disease severity. Mild patients exhibited transient type I interferon responses, while ICU patients had prolonged
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The Journal of clinical investigation, 123(8), 3383-3394 (2013-07-23)
Systemic administration of IL-12p70 has demonstrated clinical activity in cancer patients, but dose-limiting toxicities have hindered its incorporation in vaccine formulations. Here, we report on the immunological and clinical outcomes upon vaccination with CD40L/IFN-γ-matured, IL-12p70-producing DCs. 7 HLA-A*0201+ newly diagnosed
Contenido relacionado
Multiplex detection is a highly efficient tool for measuring the levels of multiple analytes in a single sample. MILLIPLEX® MAP assay panels provide a complete solution for multiplex detection of analytes within particular research areas using the bead-based Luminex® xMAP® technology. Previously, the only option for analyzing MILLIPLEX® MAP assays required the Luminex 200™ or FLEXMAP 3D® analyzers. With the launch of the MAGPIX® system, MILLIPLEX® MAP magnetic bead assays can be analyzed without the use of lasers or hydrodynamic focusing. The MAGPIX® instrument is a compact, cost-effective multiplexing system based on CCD imaging technology. The MAGPIX® instrument was specifically designed to yield comparable results to the Luminex 200™ instrument. To demonstrate similarity between the two systems, we ran parallel assays using the MILLIPLEX® MAP Human Cytokine/Chemokine Magnetic Bead Panel. Standard curve median fluorescence intensity (MFI) and sample range data are similar between
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Does the BCA-1 in HCYP2MAG-62K cross react with mouse since BCA-1 is not offered in a mouse Milliplex kit?
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