PHR1214

Methyl salicylate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: 2-Hydroxybenzoic acid methyl ester, Methyl 2-hydroxybenzoate, Oil of wintergreen, Wintergreen oil
• Fórmula lineal: 2-(HO)C₆H₄CO₂CH₃
• Número CAS: 119-36-8
• Peso molecular: 152.15
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329823221
• EC Number: 204-317-7
• Beilstein/REAXYS Number: 971516
• MDL number: MFCD00002214

Propiedades

• Nombre del producto: Methyl salicylate, Pharmaceutical Secondary Standard; Certified Reference Material
• InChI key: OSWPMRLSEDHDFF-UHFFFAOYSA-N
• InChI: 1S/C8H8O3/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5,9H,1H3
• SMILES string: COC(=O)c1ccccc1O
• grade: certified reference material; pharmaceutical secondary standard
• agency: traceable to USP 1537450
• vapor density: 5.26 (vs air)
• vapor pressure: 1 mmHg ( 54 °C)
• API family: methyl salicylate
• CofA: current certificate can be downloaded
• autoignition temp.: 847 °F
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• refractive index: n20/D 1.536 (lit.)
• bp: 222 °C (lit.)
• mp: −8-−7 °C (lit.)
• density: 1.174 g/mL at 25 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• Quality Level: 300

Descripción

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Application

Methyl salicylate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography[1][2] and voltammetry[3] techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Methyl salicylate is one of the common ingredients present in topical analgesics and rubifacients. It is prescribed for the management of minor muscle aches and pains.[4]

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC3556 in the slot below. This is an example certificate only and may not be the lot that you receive.

Información de seguridad

• pictograms: GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H302,H317,H318,H361d,H412
• pcodes: P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Sens. 1B
• Clase de almacenamiento: 10 - Combustible liquids
• wgk: WGK 2
• flash_point_f: 204.8 °F - closed cup
• flash_point_c: 96 °C - closed cup