G5146

D-(+)-Glucosa

Hybri-Max^™, powder, BioReagent, suitable for hybridoma

• Sinónimos: Dextrosa
• Fórmula empírica (notación de Hill): C₆H₁₂O₆
• Número CAS: 50-99-7
• Peso molecular: 180.16
• Beilstein/REAXYS Number: 1724615
• EC Number: 200-075-1
• MDL number: MFCD00063774
• UNSPSC Code: 12352201
• PubChem Substance ID: 24895199
• NACRES: NA.75

Propiedades

• biological source: maize
• Quality Level: 200
• grade: Hybri-Max^™
• product line: BioReagent
• assay: ≥99.5%
• form: powder
• technique(s): cell culture | hybridoma: suitable
• impurities: endotoxin, tested
• mp: 150-152 °C (lit.)
• solubility: H₂O: 2g + 15 mL (Tested)
• SMILES string: OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
• Inchi Key: WQZGKKKJIJFFOK-DVKNGEFBSA-N
• Gene Information: human ... PYGM(5837)

Descripción

General description

Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively.[1] The PYGM gene is mapped to human chromosome 11q13.1.[2]

Application

D-(+)-Glucose has been used in cell engineering.[3] It has also been used to perform oral glucose tolerance test.[4]

Biochem/physiol Actions

Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia.[1] Mutation in PYGM leads to McArdle disease, a glycogen storage disorder.[5] The PYGM gene is significantly associated with energy production.[6]

Preparation Note

The material may produce a yellowish solution if prepared at a higher concentration than 2g + 15ml.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk_germany: WGK 1
• ppe: Eyeshields, Gloves, type N95 (US)