APP
amyloid beta (A4) precursor protein
Synonyms:
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
Species:
Human APP (351), Mouse App (11820), Rat App (54226), fruit fly app (39399), chicken APP (374198), dog APP (403407), domestic cat APP (101085564), cow APP (280722), sheep APP (101111593), domestic guinea pig App (100715302)
UniProtKB ID:
Gene ID:
- Human(351) Summary: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(11820) amyloid beta (A4) precursor protein
- Rat(54226) amyloid beta (A4) precursor protein
- fruit fly(39399) approximated
- chicken(374198) amyloid beta (A4) precursor protein
- dog(403407) amyloid beta (A4) precursor protein
- domestic cat(101085564) amyloid beta (A4) precursor protein
- cow(280722) amyloid beta (A4) precursor protein
- sheep(101111593) amyloid beta (A4) precursor protein
- domestic guinea pig(100715302) amyloid beta (A4) precursor protein
- naked mole-rat(101724743) amyloid beta (A4) precursor protein
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-APP A4 Antibody, a.a. 66-81 of APP (NT) antibody produced in mouse, clone 22C11,
Species Reactivity
fish, human, monkey, pig, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Amyloid Antibody, β 1-40, Chemicon®, from rabbit,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Amyloid Beta A4 protein Antibody, clone 2D8, clone 2D8, from rat,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
western blot
Anti-Amyloid β Antibody, clone W0-2, clone WO2, from mouse,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Amyloid β40 Antibody, clone G2-10, clone G2-10, from mouse,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species