APP
amyloid beta (A4) precursor protein
Synonimy:
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
Gatunek:
Human APP (351), Mouse App (11820), Rat App (54226), fruit fly app (39399), chicken APP (374198), dog APP (403407), domestic cat APP (101085564), cow APP (280722), sheep APP (101111593), domestic guinea pig App (100715302)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(351) Summary: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(11820) amyloid beta (A4) precursor protein
- Rat(54226) amyloid beta (A4) precursor protein
- fruit fly(39399) approximated
- chicken(374198) amyloid beta (A4) precursor protein
- dog(403407) amyloid beta (A4) precursor protein
- domestic cat(101085564) amyloid beta (A4) precursor protein
- cow(280722) amyloid beta (A4) precursor protein
- sheep(101111593) amyloid beta (A4) precursor protein
- domestic guinea pig(100715302) amyloid beta (A4) precursor protein
- naked mole-rat(101724743) amyloid beta (A4) precursor protein
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ELISA
Numer produktu
Opis
Gatunek
Human APP / Amyloid Beta A4 Protein ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Gatunek
human
Small Molecule - Antagonist
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Beta-Amyloid 1-42 Antibody, Chemicon®, from rabbit,
Reaktywność gatunkowa
chicken, human, mouse
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APP A4 Antibody, clone 22C11 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
canine, human, monkey, mouse, porcine, rat
Zastosowanie
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APP A4 Antibody, a.a. 66-81 of APP {NT}, clone 22C11, clone 22C11, Chemicon®, from mouse,
Reaktywność gatunkowa
canine, fish, human, monkey, mouse, pig, rat
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Przeciwciało anty-APP A4, a.a. 66-81 APP {NT} Przeciwciało, klon 22C11, koniugat Alexa Fluor™ 647, clone 22C11, from mouse, ALEXA FLUOR™ 647,
Reaktywność gatunkowa
canine, fish, human, monkey, mouse, porcine, rat
Zastosowanie
immunocytochemistry
Przeciwciało przeciw białku prekursorowemu amyloidu, A4(695), klon 1.D5, clone 1.D5, Chemicon®, from mouse,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Proteins
Numer produktu
Opis
Gatunek
Amyloid Precursor Protein β, Secreted human, recombinant, expressed in E. coli (N-terminal histidine tagged), solution,
Gatunek
human