Good quality antibiotic for research. Already disolved so it makes it easier to use but difficult to store for long term
G8168
G418 disulfate salt
solution, non-animal origin, suitable for cell culture, BioReagent
1 of 2 reviewers took part in a promotion
Synonym(s):
Antibiotic G418
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| Size/SKU | Availability | Price |
|---|---|---|
10 mL | Available to ship TODAYfromMILWAUKEE | $130.00 |
50 mL | Available to ship TODAYfromMILWAUKEE | $571.00 |
100 mL | Available to ship TODAYfromMILWAUKEE | $791.00 |
About This Item
Empirical Formula (Hill Notation):
C20H40N4O10 · 2H2SO4
CAS Number:
Molecular Weight:
692.71
MDL number:
UNSPSC Code:
12352207
PubChem Substance ID:
NACRES:
NA.76
Product Name
G 418 disulfate salt solution, 50 mg/mL in H2O, 0.1 μm filtered, BioReagent, suitable for cell culture
biological source
Micromonospora echinospora
Quality Segment
sterility
0.1 μm filtered
product line
BioReagent
form
solution
potency
50-60 mg per mL
mol wt
692.7
packaging
pkg of 10 and 100 mL
concentration
50 mg/mL in H2O
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
colorless
solubility
H2O: 50 mg/mL, clear
antibiotic activity spectrum
parasites
mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](OC[C@@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O
InChI
1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1
InChI key
UHEPSJJJMTWUCP-NKCAIAFTSA-N
General description
Chemical structure: aminoglycoside
Application
G418 disulfate is an aminoglycoside antibiotic similar in structure to gentamicin used for selection and maintenance of prokaryotic and eukaryotic cells. Optimal concentrations for selection and maintenance vary by cell lines. Bacteria and algae require 5 μg/mL or less while animal cells may require 300-500 μg/mL.
Biochem/physiol Actions
Mode of Action: G418 blocks polypeptide synthesis and protein elongation by inhibiting synthesis at the 70S and 80S ribosomes.
Antimicrobial Spectrum: G418 selects for cells stably transfected with an iNOS promoter construct and neomycin resistance gene and shows activity against protozoa and helminthes.
Antimicrobial Spectrum: G418 selects for cells stably transfected with an iNOS promoter construct and neomycin resistance gene and shows activity against protozoa and helminthes.
Disclaimer
The product is stable for two years when stored at 2-8°C.
1 of 1
This Item | |||
|---|---|---|---|
| description 50 mg/mL in H2O, 0.1 μm filtered, BioReagent, suitable for cell culture | description powder, BioReagent, suitable for cell culture | description potency: ≥720 μg per mg (dried basis) | description with 200 mM L-glutamine and 5 mg gentamicin per mL in tissue culture grade water, liquid, 0.1 μm filtered, BioReagent, suitable for cell culture |
| mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action protein synthesis | interferes | mode of action protein synthesis | interferes |
| antibiotic activity spectrum parasites | antibiotic activity spectrum Gram-negative bacteria | antibiotic activity spectrum Gram-negative bacteria | antibiotic activity spectrum mycoplasma, Gram-positive bacteria, Gram-negative bacteria |
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) cell culture | mammalian: suitable |
| product line BioReagent | product line BioReagent | product line - | product line BioReagent |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 300 |
| form solution | form powder | form powder | form liquid |
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Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
12 - Non Combustible Liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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