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A0664

4-Aminobutylphosphonic acid

≥99%

Sinónimos:

P-(4-aminobutyl)-phosphonic acid

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Acerca de este artículo

Fórmula empírica (notación de Hill):
C4H12NO3P
Número CAS:
35622-27-6
Peso molecular:
153.12
NACRES:
NA.26
PubChem Substance ID:
24890444
UNSPSC Code:
12352106
MDL number:
MFCD00063426
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Quality Level

100

assay

≥99%

form

powder

color

white

application(s)

detection

SMILES string

NCCCCP(O)(O)=O

InChI

1S/C4H12NO3P/c5-3-1-2-4-9(6,7)8/h1-5H2,(H2,6,7,8)

InChI key

IDPXFPYGZRMMKZ-UHFFFAOYSA-N

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Este artículo
P29006M8883SML0475
4-Aminobutylphosphonic acid ≥99%

Sigma-Aldrich

A0664

4-Aminobutylphosphonic acid

Phenylphosphonic acid 98%

Sigma-Aldrich

P29006

Phenylphosphonic acid

4-Methylumbelliferyl phosphate phosphatase substrate

Sigma-Aldrich

M8883

4-Methylumbelliferyl phosphate

CGP36742 ≥97% (NMR)

Sigma-Aldrich

SML0475

CGP36742

form

powder

form

crystals

form

powder

form

powder

assay

≥99%

assay

98%

assay

≥98% (HPLC)

assay

≥97% (NMR)

color

white

color

-

color

-

color

white to beige

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

application(s)

detection

application(s)

-

application(s)

-

application(s)

-

Biochem/physiol Actions

4-Aminobutylphosphonic acid, a GABA B receptor ligand, is used in studies on the regulation of prolactin (PRL) secretion and differential GABA receptor research.
4-aminobutylphosphonic acid, the phosphonic acid analogue of delta-aminovaleric acid, inhibits gamma-aminobutyric acid B (GABA-B receptor) binding without influencing either isoproterenol- or forskolin-stimulated cyclic AMP production.

Other Notes

Analog of δ-aminovaleric acid

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0000450854
0000450854
0000436601
0000436601
0000418067

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H P De Koning et al.
Endocrinology, 132(2), 674-681 (1993-02-01)
The activity of many endocrine cells is regulated by gamma-aminobutyric acid (GABA). The effects of GABA are mediated by GABAA and/or GABAB receptors. While GABAB receptors in the central nervous system have now been extensively characterized, little is known of
Oktay Yildirim et al.
International journal of molecular sciences, 11(3), 1162-1179 (2010-05-19)
FePt nanoparticles (NPs) were assembled on aluminum oxide substrates, and their ferromagnetic properties were studied before and after thermal annealing. For the first time, phosph(on)ates were used as an adsorbate to form self-assembled monolayers (SAMs) on alumina to direct the
J Ong et al.
Naunyn-Schmiedeberg's archives of pharmacology, 357(4), 408-412 (1998-05-30)
The effects of five phosphonic derivatives of GABA on the release of [3H]-GABA from rat neocortical slices, preloaded with [3H]-GABA, were investigated. Phaclofen and 4-aminobutylphosphonic acid (4-ABPA) increased the overflow of [3H] evoked by electrical stimulation (2 Hz) in a
L S Wong et al.
Pharmacology, biochemistry, and behavior, 38(4), 829-835 (1991-04-01)
The application of 1.2 and 12.0 micrograms/side of the GABAA receptor agonist 3-aminopropane sulphonic acid bilaterally into the nucleus accumbens (Acb) of rats nonsignificantly depressed locomotor activity as assessed in automated Animex activity cages, while the highest dose (60 micrograms/side)
R W Scherer et al.
Brain research bulletin, 21(3), 439-443 (1988-09-01)
Activation of GABAB receptors augments neurotransmitter-stimulated cyclic AMP accumulation while inhibiting forskolin-mediated second messenger production. Previous studies have revealed that GABAB receptors are associated with a pertussis toxin sensitive G protein, such as Gi. While such a linkage is consistent
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Número de artículo de comercio global

SKUGTIN
A0664-250MG04061832414560

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