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Anti-Matrix Metalloproteinase-28, Propeptide Region antibody produced in rabbit

Name: Anti-Matrix Metalloproteinase-28, Propeptide Region antibody produced in rabbit
Brand: SIGMA
Price: 655 USD
Availability: InStock

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-Epilysin, Anti-MMP-28

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Size/SKU	Availability	Price
100 μg	Check Cart for Availability	$655.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD04040453

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

$655.00

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Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

human

concentration

~1 mg/mL

technique(s)

western blot: 1:1,000

UniProt accession no.

Q9H239

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MMP28(79148)

Description

General description

Matrix metalloproteinase-28 (MMP-28) is expressed in normal tissues like the epidermis of the skin, brain, lungs and intestine. It possesses an activation sequence and a pro-domain. The gene encoding it is localized on human chromosome 17q11.2 and has eight exons.

Immunogen

synthetic peptide corresponding to the propeptide region of human matrix metalloproteinase-28.

Biochem/physiol Actions

By immunoblotting against the reduced protein, the antibody identifies bands at 62 kDa and 58 kDa, as well as breakdown products at 50 kDa, 48 kDa, and 46 kDa. At higher antibody concentrations, the antibody also detects a 70 kDa band in rat and mouse tissues.

Matrix metalloproteinase-28 (MMP-28) may have a role in modulating matrix composition. It is an endopeptidase which degrades casein and mediates epithelial to mesenchymal transition. MMP-28 aids in progression of tumors and is overexpressed in gastric carcinomas.

Physical form

Solution in 0.01 M phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	M6559	M8692	M6057
Sigma-Aldrich M5191 Anti-Matrix Metalloproteinase-28, Propeptide Region antibody produced in rabbit	Sigma-Aldrich M6559 Anti-Matrix Metalloproteinase-24, Cytoplasmic antibody produced in rabbit	Sigma-Aldrich M8692 Anti-Matrix Metalloproteinase-21, Hinge Region antibody produced in rabbit	Sigma-Aldrich M6057 Anti-Matrix Metalloproteinase-12, Propeptide Region antibody produced in rabbit
description ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution	description ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution	description affinity isolated antibody, buffered aqueous glycerol solution	description ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
shipped in wet ice	shipped in wet ice	shipped in wet ice	shipped in wet ice
species reactivity human	species reactivity mouse, human	species reactivity rat, human, Xenopus, mouse	species reactivity human

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

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